Kahle KT - Search Results

1

Current view on the functional regulation of the neuronal K(+)-Cl(-) cotransporter KCC2.

Medina I, Friedel P, Rivera C, Kahle KT, Kourdougli N, Uvarov P, Pellegrino C. Medina I, et al. Among authors: kahle kt. Front Cell Neurosci. 2014 Feb 6;8:27. doi: 10.3389/fncel.2014.00027. eCollection 2014. Front Cell Neurosci. 2014. PMID: 24567703 Free PMC article. Review.

2

Limitations of Current GABA Agonists in Neonatal Seizures: Toward GABA Modulation Via the Targeting of Neuronal Cl(-) Transport.

Khanna A, Walcott BP, Kahle KT. Khanna A, et al. Among authors: kahle kt. Front Neurol. 2013 Jun 25;4:78. doi: 10.3389/fneur.2013.00078. eCollection 2013. Front Neurol. 2013. PMID: 23805124 Free PMC article.

3

Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2.

Kahle KT, Deeb TZ, Puskarjov M, Silayeva L, Liang B, Kaila K, Moss SJ. Kahle KT, et al. Trends Neurosci. 2013 Dec;36(12):726-737. doi: 10.1016/j.tins.2013.08.006. Epub 2013 Oct 15. Trends Neurosci. 2013. PMID: 24139641 Free PMC article. Review.

4

Genetically encoded impairment of neuronal KCC2 cotransporter function in human idiopathic generalized epilepsy.

Kahle KT, Merner ND, Friedel P, Silayeva L, Liang B, Khanna A, Shang Y, Lachance-Touchette P, Bourassa C, Levert A, Dion PA, Walcott B, Spiegelman D, Dionne-Laporte A, Hodgkinson A, Awadalla P, Nikbakht H, Majewski J, Cossette P, Deeb TZ, Moss SJ, Medina I, Rouleau GA. Kahle KT, et al. EMBO Rep. 2014 Jul;15(7):766-74. doi: 10.15252/embr.201438840. Epub 2014 Jun 13. EMBO Rep. 2014. PMID: 24928908 Free PMC article.

5

WNK1-regulated inhibitory phosphorylation of the KCC2 cotransporter maintains the depolarizing action of GABA in immature neurons.

Friedel P, Kahle KT, Zhang J, Hertz N, Pisella LI, Buhler E, Schaller F, Duan J, Khanna AR, Bishop PN, Shokat KM, Medina I. Friedel P, et al. Among authors: kahle kt. Sci Signal. 2015 Jun 30;8(383):ra65. doi: 10.1126/scisignal.aaa0354. Sci Signal. 2015. PMID: 26126716

6

Regulated phosphorylation of the K-Cl cotransporter KCC3 is a molecular switch of intracellular potassium content and cell volume homeostasis.

Adragna NC, Ravilla NB, Lauf PK, Begum G, Khanna AR, Sun D, Kahle KT. Adragna NC, et al. Among authors: kahle kt. Front Cell Neurosci. 2015 Jul 9;9:255. doi: 10.3389/fncel.2015.00255. eCollection 2015. Front Cell Neurosci. 2015. PMID: 26217182 Free PMC article.

7

Regulatory domain or CpG site variation in SLC12A5, encoding the chloride transporter KCC2, in human autism and schizophrenia.

Merner ND, Chandler MR, Bourassa C, Liang B, Khanna AR, Dion P, Rouleau GA, Kahle KT. Merner ND, et al. Among authors: kahle kt. Front Cell Neurosci. 2015 Oct 12;9:386. doi: 10.3389/fncel.2015.00386. eCollection 2015. Front Cell Neurosci. 2015. PMID: 26528127 Free PMC article.

8

Impaired regulation of KCC2 phosphorylation leads to neuronal network dysfunction and neurodevelopmental pathology.

Pisella LI, Gaiarsa JL, Diabira D, Zhang J, Khalilov I, Duan J, Kahle KT, Medina I. Pisella LI, et al. Among authors: kahle kt. Sci Signal. 2019 Oct 15;12(603):eaay0300. doi: 10.1126/scisignal.aay0300. Sci Signal. 2019. PMID: 31615899 Free PMC article.

9

Progressive NKCC1-dependent neuronal chloride accumulation during neonatal seizures.

Dzhala VI, Kuchibhotla KV, Glykys JC, Kahle KT, Swiercz WB, Feng G, Kuner T, Augustine GJ, Bacskai BJ, Staley KJ. Dzhala VI, et al. Among authors: kahle kt. J Neurosci. 2010 Sep 1;30(35):11745-61. doi: 10.1523/JNEUROSCI.1769-10.2010. J Neurosci. 2010. PMID: 20810895 Free PMC article.

10

Local impermeant anions establish the neuronal chloride concentration.

Glykys J, Dzhala V, Egawa K, Balena T, Saponjian Y, Kuchibhotla KV, Bacskai BJ, Kahle KT, Zeuthen T, Staley KJ. Glykys J, et al. Among authors: kahle kt. Science. 2014 Feb 7;343(6171):670-5. doi: 10.1126/science.1245423. Science. 2014. PMID: 24503855 Free PMC article.

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