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Control of innate immunity by the cGAS-STING pathway.
Mosallanejad K, Kagan JC. Mosallanejad K, et al. Among authors: kagan jc. Immunol Cell Biol. 2022 Jul;100(6):409-423. doi: 10.1111/imcb.12555. Epub 2022 May 25. Immunol Cell Biol. 2022. PMID: 35485309 Free PMC article. Review.
Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING.
Brown Harding H, Kwaku GN, Reardon CM, Khan NS, Zamith-Miranda D, Zarnowski R, Tam JM, Bohaen CK, Richey L, Mosallanejad K, Crossen AJ, Reedy JL, Ward RA, Vargas-Blanco DA, Basham KJ, Bhattacharyya RP, Nett JE, Mansour MK, van de Veerdonk FL, Kumar V, Kagan JC, Andes DR, Nosanchuk JD, Vyas JM. Brown Harding H, et al. Among authors: kagan jc. Nat Microbiol. 2024 Jan;9(1):95-107. doi: 10.1038/s41564-023-01546-0. Epub 2024 Jan 2. Nat Microbiol. 2024. PMID: 38168615 Free PMC article.
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D.
Du G, Healy LB, David L, Walker C, El-Baba TJ, Lutomski CA, Goh B, Gu B, Pi X, Devant P, Fontana P, Dong Y, Ma X, Miao R, Balasubramanian A, Puthenveetil R, Banerjee A, Luo HR, Kagan JC, Oh SF, Robinson CV, Lieberman J, Wu H. Du G, et al. Among authors: kagan jc. Nature. 2024 Apr 10. doi: 10.1038/s41586-024-07373-5. Online ahead of print. Nature. 2024. PMID: 38599239
STING-dependent translation inhibition restricts RNA virus replication.
Franz KM, Neidermyer WJ, Tan YJ, Whelan SPJ, Kagan JC. Franz KM, et al. Among authors: kagan jc. Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):E2058-E2067. doi: 10.1073/pnas.1716937115. Epub 2018 Feb 12. Proc Natl Acad Sci U S A. 2018. PMID: 29440426 Free PMC article.
Peroxisomes are signaling platforms for antiviral innate immunity.
Dixit E, Boulant S, Zhang Y, Lee AS, Odendall C, Shum B, Hacohen N, Chen ZJ, Whelan SP, Fransen M, Nibert ML, Superti-Furga G, Kagan JC. Dixit E, et al. Among authors: kagan jc. Cell. 2010 May 14;141(4):668-81. doi: 10.1016/j.cell.2010.04.018. Epub 2010 May 6. Cell. 2010. PMID: 20451243 Free PMC article.
126 results