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HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation.
Magupalli VG, Negro R, Tian Y, Hauenstein AV, Di Caprio G, Skillern W, Deng Q, Orning P, Alam HB, Maliga Z, Sharif H, Hu JJ, Evavold CL, Kagan JC, Schmidt FI, Fitzgerald KA, Kirchhausen T, Li Y, Wu H. Magupalli VG, et al. Among authors: kagan jc. Science. 2020 Sep 18;369(6510):eaas8995. doi: 10.1126/science.aas8995. Science. 2020. PMID: 32943500 Free PMC article.
Immunology. Sensing endotoxins from within.
Kagan JC. Kagan JC. Science. 2013 Sep 13;341(6151):1184-5. doi: 10.1126/science.1243939. Science. 2013. PMID: 24031006 Free PMC article. No abstract available.
Control of the innate immune response by the mevalonate pathway.
Akula MK, Shi M, Jiang Z, Foster CE, Miao D, Li AS, Zhang X, Gavin RM, Forde SD, Germain G, Carpenter S, Rosadini CV, Gritsman K, Chae JJ, Hampton R, Silverman N, Gravallese EM, Kagan JC, Fitzgerald KA, Kastner DL, Golenbock DT, Bergo MO, Wang D. Akula MK, et al. Among authors: kagan jc. Nat Immunol. 2016 Aug;17(8):922-9. doi: 10.1038/ni.3487. Epub 2016 Jun 6. Nat Immunol. 2016. PMID: 27270400 Free PMC article.
How Inflammasomes Inform Adaptive Immunity.
Evavold CL, Kagan JC. Evavold CL, et al. Among authors: kagan jc. J Mol Biol. 2018 Jan 19;430(2):217-237. doi: 10.1016/j.jmb.2017.09.019. Epub 2017 Oct 5. J Mol Biol. 2018. PMID: 28987733 Free PMC article. Review.
151 results