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The nuclear pore proteins Nup88/214 and T-cell acute lymphatic leukemia-associated NUP214 fusion proteins regulate Notch signaling.
Kindermann B, Valkova C, Krämer A, Perner B, Engelmann C, Behrendt L, Kritsch D, Jungnickel B, Kehlenbach RH, Oswald F, Englert C, Kaether C. Kindermann B, et al. Among authors: kaether c. J Biol Chem. 2019 Aug 2;294(31):11741-11750. doi: 10.1074/jbc.RA118.006357. Epub 2019 Jun 11. J Biol Chem. 2019. PMID: 31186352 Free PMC article.
Notch1 signaling is mediated by importins alpha 3, 4, and 7.
Huenniger K, Krämer A, Soom M, Chang I, Köhler M, Depping R, Kehlenbach RH, Kaether C. Huenniger K, et al. Among authors: kaether c. Cell Mol Life Sci. 2010 Sep;67(18):3187-96. doi: 10.1007/s00018-010-0378-7. Epub 2010 May 8. Cell Mol Life Sci. 2010. PMID: 20454918 Free PMC article.
Small molecules intercept Notch signaling and the early secretory pathway.
Krämer A, Mentrup T, Kleizen B, Rivera-Milla E, Reichenbach D, Enzensperger C, Nohl R, Täuscher E, Görls H, Ploubidou A, Englert C, Werz O, Arndt HD, Kaether C. Krämer A, et al. Among authors: kaether c. Nat Chem Biol. 2013 Nov;9(11):731-8. doi: 10.1038/nchembio.1356. Epub 2013 Sep 29. Nat Chem Biol. 2013. PMID: 24077179
64 results