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A bedside to bench study of anti-PD-1, anti-CD40, and anti-CSF1R indicates that more is not necessarily better.
Djureinovic D, Weiss SA, Krykbaeva I, Qu R, Vathiotis I, Moutafi M, Zhang L, Perdigoto AL, Wei W, Anderson G, Damsky W, Hurwitz M, Johnson B, Schoenfeld D, Mahajan A, Hsu F, Miller-Jensen K, Kluger Y, Sznol M, Kaech SM, Bosenberg M, Jilaveanu LB, Kluger HM. Djureinovic D, et al. Among authors: kaech sm. Mol Cancer. 2023 Nov 14;22(1):182. doi: 10.1186/s12943-023-01884-x. Mol Cancer. 2023. PMID: 37964379 Free PMC article.
Drug Sensitivity and Allele Specificity of First-Line Osimertinib Resistance EGFR Mutations.
Starrett JH, Guernet AA, Cuomo ME, Poels KE, van Alderwerelt van Rosenburgh IK, Nagelberg A, Farnsworth D, Price KS, Khan H, Ashtekar KD, Gaefele M, Ayeni D, Stewart TF, Kuhlmann A, Kaech SM, Unni AM, Homer R, Lockwood WW, Michor F, Goldberg SB, Lemmon MA, Smith PD, Cross DAE, Politi K. Starrett JH, et al. Among authors: kaech sm. Cancer Res. 2020 May 15;80(10):2017-2030. doi: 10.1158/0008-5472.CAN-19-3819. Epub 2020 Mar 19. Cancer Res. 2020. PMID: 32193290 Free PMC article.
Parallels Between the Antiviral State and the Irradiated State.
McGee HM, Marciscano AE, Campbell AM, Monjazeb AM, Kaech SM, Teijaro JR. McGee HM, et al. Among authors: kaech sm. J Natl Cancer Inst. 2021 Aug 2;113(8):969-979. doi: 10.1093/jnci/djaa190. J Natl Cancer Inst. 2021. PMID: 33252657 Free PMC article.
CTLA-4 blockade induces a microglia-Th1 cell partnership that stimulates microglia phagocytosis and anti-tumor function in glioblastoma.
Chen D, Varanasi SK, Hara T, Traina K, Sun M, McDonald B, Farsakoglu Y, Clanton J, Xu S, Garcia-Rivera L, Mann TH, Du V, Chung HK, Xu Z, Tripple V, Casillas E, Ma S, O'Connor C, Yang Q, Zheng Y, Hunter T, Lemke G, Kaech SM. Chen D, et al. Among authors: kaech sm. Immunity. 2023 Sep 12;56(9):2086-2104.e8. doi: 10.1016/j.immuni.2023.07.015. Epub 2023 Aug 11. Immunity. 2023. PMID: 37572655
Eicosanoids in the pancreatic tumor microenvironment - a multicellular, multifaceted progression.
Gubbala VB, Jytosana N, Trinh VQ, Maurer HC, Naeem RF, Lytle NK, Ma Z, Zhao S, Lin W, Han H, Shi Y, Hunter T, Singh PK, Olive KP, Tan MCB, Kaech SM, Wahl GM, DelGiorno KE. Gubbala VB, et al. Among authors: kaech sm. Gastro Hep Adv. 2022;1(4):682-697. doi: 10.1016/j.gastha.2022.02.007. Epub 2022 Jun 11. Gastro Hep Adv. 2022. PMID: 36277993 Free PMC article.
161 results