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Pivotal role of inter-organ aspartate metabolism for treatment of mitochondrial aspartate-glutamate carrier 2 (citrin) deficiency, based on the mouse model.
Saheki T, Moriyama M, Kuroda E, Funahashi A, Yasuda I, Setogawa Y, Gao Q, Ushikai M, Furuie S, Yamamura KI, Takano K, Nakamura Y, Eto K, Kadowaki T, Sinasac DS, Furukawa T, Horiuchi M, Tai YH. Saheki T, et al. Among authors: kadowaki t. Sci Rep. 2019 Mar 12;9(1):4179. doi: 10.1038/s41598-019-39627-y. Sci Rep. 2019. PMID: 30862943 Free PMC article.
Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice.
Yamauchi T, Oike Y, Kamon J, Waki H, Komeda K, Tsuchida A, Date Y, Li MX, Miki H, Akanuma Y, Nagai R, Kimura S, Saheki T, Nakazato M, Naitoh T, Yamamura K, Kadowaki T. Yamauchi T, et al. Among authors: kadowaki t. Nat Genet. 2002 Feb;30(2):221-6. doi: 10.1038/ng829. Epub 2002 Jan 30. Nat Genet. 2002. PMID: 11818964
Disruption of adiponectin causes insulin resistance and neointimal formation.
Kubota N, Terauchi Y, Yamauchi T, Kubota T, Moroi M, Matsui J, Eto K, Yamashita T, Kamon J, Satoh H, Yano W, Froguel P, Nagai R, Kimura S, Kadowaki T, Noda T. Kubota N, et al. Among authors: kadowaki t. J Biol Chem. 2002 Jul 19;277(29):25863-6. doi: 10.1074/jbc.C200251200. Epub 2002 May 24. J Biol Chem. 2002. PMID: 12032136 Free article.
Switch to anaerobic glucose metabolism with NADH accumulation in the beta-cell model of mitochondrial diabetes. Characteristics of betaHC9 cells deficient in mitochondrial DNA transcription.
Noda M, Yamashita S, Takahashi N, Eto K, Shen LM, Izumi K, Daniel S, Tsubamoto Y, Nemoto T, Iino M, Kasai H, Sharp GW, Kadowaki T. Noda M, et al. Among authors: kadowaki t. J Biol Chem. 2002 Nov 1;277(44):41817-26. doi: 10.1074/jbc.M207690200. Epub 2002 Aug 6. J Biol Chem. 2002. PMID: 12169697 Free article.
To elucidate the mechanism underlying diabetes caused by mitochondrial gene mutations, we created a model by applying 0.4 microg/ml ethidium bromide (EtBr) to the murine pancreatic beta cell line betaHC9; in this model, transcription of mitochondrial DNA, but not that of nuclear …
To elucidate the mechanism underlying diabetes caused by mitochondrial gene mutations, we created a model by applying 0.4 microg/ml ethidium …
[Glucokinase].
Eto K, Kadowaki T. Eto K, et al. Among authors: kadowaki t. Nihon Rinsho. 2002 Jul;60 Suppl 7:523-34. Nihon Rinsho. 2002. PMID: 12238093 Review. Japanese. No abstract available.
Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis.
Yamauchi T, Kamon J, Waki H, Imai Y, Shimozawa N, Hioki K, Uchida S, Ito Y, Takakuwa K, Matsui J, Takata M, Eto K, Terauchi Y, Komeda K, Tsunoda M, Murakami K, Ohnishi Y, Naitoh T, Yamamura K, Ueyama Y, Froguel P, Kimura S, Nagai R, Kadowaki T. Yamauchi T, et al. Among authors: kadowaki t. J Biol Chem. 2003 Jan 24;278(4):2461-8. doi: 10.1074/jbc.M209033200. Epub 2002 Nov 12. J Biol Chem. 2003. PMID: 12431986 Free article.
1,567 results