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SAR of Novel 3-Arylisoquinolinones: meta-Substitution on the Aryl Ring Dramatically Enhances Antiproliferative Activity through Binding to Microtubules.
Elhemely MA, Belgath AA, El-Sayed S, Burusco KK, Kadirvel M, Tirella A, Finegan K, Bryce RA, Stratford IJ, Freeman S. Elhemely MA, et al. Among authors: kadirvel m. J Med Chem. 2022 Mar 24;65(6):4783-4797. doi: 10.1021/acs.jmedchem.1c01936. Epub 2022 Mar 15. J Med Chem. 2022. PMID: 35290041 Free PMC article.
Impact of long-term quorum sensing inhibition on uropathogenic Escherichia coli.
Henly EL, Norris K, Rawson K, Zoulias N, Jaques L, Chirila PG, Parkin KL, Kadirvel M, Whiteoak C, Lacey MM, Smith TJ, Forbes S. Henly EL, et al. Among authors: kadirvel m. J Antimicrob Chemother. 2021 Mar 12;76(4):909-919. doi: 10.1093/jac/dkaa517. J Antimicrob Chemother. 2021. PMID: 33406232
Evaluation of analogues of furan-amidines as inhibitors of NQO2.
Alnabulsi S, Hussein B, Santina E, Alsalahat I, Kadirvel M, Magwaza RN, Bryce RA, Schwalbe CH, Baldwin AG, Russo I, Stratford IJ, Freeman S. Alnabulsi S, et al. Among authors: kadirvel m. Bioorg Med Chem Lett. 2018 May 1;28(8):1292-1297. doi: 10.1016/j.bmcl.2018.03.025. Epub 2018 Mar 12. Bioorg Med Chem Lett. 2018. PMID: 29567345
Boron-Based Inhibitors of the NLRP3 Inflammasome.
Baldwin AG, Rivers-Auty J, Daniels MJD, White CS, Schwalbe CH, Schilling T, Hammadi H, Jaiyong P, Spencer NG, England H, Luheshi NM, Kadirvel M, Lawrence CB, Rothwell NJ, Harte MK, Bryce RA, Allan SM, Eder C, Freeman S, Brough D. Baldwin AG, et al. Among authors: kadirvel m. Cell Chem Biol. 2017 Nov 16;24(11):1321-1335.e5. doi: 10.1016/j.chembiol.2017.08.011. Epub 2017 Sep 21. Cell Chem Biol. 2017. PMID: 28943355 Free PMC article.
Development & automation of a novel [(18)F]F prosthetic group, 2-[(18)F]-fluoro-3-pyridinecarboxaldehyde, and its application to an amino(oxy)-functionalised Aβ peptide.
Morris O, Gregory J, Kadirvel M, Henderson F, Blykers A, McMahon A, Taylor M, Allsop D, Allan S, Grigg J, Boutin H, Prenant C. Morris O, et al. Among authors: kadirvel m. Appl Radiat Isot. 2016 Oct;116:120-7. doi: 10.1016/j.apradiso.2016.07.023. Epub 2016 Jul 27. Appl Radiat Isot. 2016. PMID: 27518217 Free PMC article.
19 results