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Osteocyte necrosis triggers osteoclast-mediated bone loss through macrophage-inducible C-type lectin.
Andreev D, Liu M, Weidner D, Kachler K, Faas M, Grüneboom A, Schlötzer-Schrehardt U, Muñoz LE, Steffen U, Grötsch B, Killy B, Krönke G, Luebke AM, Niemeier A, Wehrhan F, Lang R, Schett G, Bozec A. Andreev D, et al. Among authors: kachler k. J Clin Invest. 2020 Sep 1;130(9):4811-4830. doi: 10.1172/JCI134214. J Clin Invest. 2020. PMID: 32773408 Free PMC article.
Regulatory eosinophils induce the resolution of experimental arthritis and appear in remission state of human rheumatoid arthritis.
Andreev D, Liu M, Kachler K, Llerins Perez M, Kirchner P, Kölle J, Gießl A, Rauber S, Song R, Aust O, Grüneboom A, Kleyer A, Cañete JD, Ekici A, Ramming A, Finotto S, Schett G, Bozec A. Andreev D, et al. Among authors: kachler k. Ann Rheum Dis. 2021 Apr;80(4):451-468. doi: 10.1136/annrheumdis-2020-218902. Epub 2020 Nov 4. Ann Rheum Dis. 2021. PMID: 33148700
A new platform for autoimmune diseases. Inducing tolerance with liposomes encapsulating autoantigens.
Almenara-Fuentes L, Rodriguez-Fernandez S, Rosell-Mases E, Kachler K, You A, Salvado M, Andreev D, Steffen U, Bang H, Bozec A, Schett G, Le Panse R, Verdaguer J, Dalmases M, Rodriguez-Vidal S, Barneda-Zahonero B, Vives-Pi M. Almenara-Fuentes L, et al. Among authors: kachler k. Nanomedicine. 2023 Feb;48:102635. doi: 10.1016/j.nano.2022.102635. Epub 2022 Dec 5. Nanomedicine. 2023. PMID: 36481472 Free article.
L-arginine metabolism inhibits arthritis and inflammatory bone loss.
Cao S, Li Y, Song R, Meng X, Fuchs M, Liang C, Kachler K, Meng X, Wen J, Schlötzer-Schrehardt U, Taudte V, Gessner A, Kunz M, Schleicher U, Zaiss MM, Kastbom A, Chen X, Schett G, Bozec A. Cao S, et al. Among authors: kachler k. Ann Rheum Dis. 2024 Jan 2;83(1):72-87. doi: 10.1136/ard-2022-223626. Ann Rheum Dis. 2024. PMID: 37775153 Free PMC article.
IL-9 Producing Tumor-Infiltrating Lymphocytes and Treg Subsets Drive Immune Escape of Tumor Cells in Non-Small Cell Lung Cancer.
Heim L, Yang Z, Tausche P, Hohenberger K, Chiriac MT, Koelle J, Geppert CI, Kachler K, Miksch S, Graser A, Friedrich J, Kharwadkar R, Rieker RJ, Trufa DI, Sirbu H, Neurath MF, Kaplan MH, Finotto S. Heim L, et al. Among authors: kachler k. Front Immunol. 2022 Apr 20;13:859738. doi: 10.3389/fimmu.2022.859738. eCollection 2022. Front Immunol. 2022. PMID: 35514957 Free PMC article.
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