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2021 3
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Brain-Derived CCN3 Is An Osteoanabolic Hormone That Sustains Bone in Lactating Females.
Babey ME, Krause WC, Herber CB, Chen K, Nikkanen J, Rodriquez R, Zhang X, Castro-Navarro F, Wang Y, Villeda S, Lane NE, Scheller EL, Chan CKF, Ambrosi TH, Ingraham HA. Babey ME, et al. bioRxiv [Preprint]. 2023 Nov 16:2023.08.28.554707. doi: 10.1101/2023.08.28.554707. bioRxiv. 2023. PMID: 37693376 Free PMC article. Preprint.
Purification and functional characterization of novel human skeletal stem cell lineages.
Hoover MY, Ambrosi TH, Steininger HM, Koepke LS, Wang Y, Zhao L, Murphy MP, Alam AA, Arouge EJ, Butler MGK, Takematsu E, Stavitsky SP, Hu S, Sahoo D, Sinha R, Morri M, Neff N, Bishop J, Gardner M, Goodman S, Longaker M, Chan CKF. Hoover MY, et al. Nat Protoc. 2023 Jul;18(7):2256-2282. doi: 10.1038/s41596-023-00836-5. Epub 2023 Jun 14. Nat Protoc. 2023. PMID: 37316563 Free PMC article. Review.
A seed-and-soil theory for blood ageing.
Ambrosi TH, Chan CKF. Ambrosi TH, et al. Nat Cell Biol. 2023 Jan;25(1):9-11. doi: 10.1038/s41556-022-01062-z. Nat Cell Biol. 2023. PMID: 36650380 Free PMC article.
Sexually dimorphic estrogen sensing in skeletal stem cells controls skeletal regeneration.
Andrew TW, Koepke LS, Wang Y, Lopez M, Steininger H, Struck D, Boyko T, Ambrosi TH, Tong X, Sun Y, Gulati GS, Murphy MP, Marecic O, Telvin R, Schallmoser K, Strunk D, Seita J, Goodman SB, Yang F, Longaker MT, Yang GP, Chan CKF. Andrew TW, et al. Nat Commun. 2022 Oct 30;13(1):6491. doi: 10.1038/s41467-022-34063-5. Nat Commun. 2022. PMID: 36310174 Free PMC article.
Cross-species comparisons reveal resistance of human skeletal stem cells to inhibition by non-steroidal anti-inflammatory drugs.
Goodnough LH, Ambrosi TH, Steininger HM, Butler MGK, Hoover MY, Choo H, Van Rysselberghe NL, Bellino MJ, Bishop JA, Gardner MJ, Chan CKF. Goodnough LH, et al. Front Endocrinol (Lausanne). 2022 Aug 25;13:924927. doi: 10.3389/fendo.2022.924927. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36093067 Free PMC article.
Aged skeletal stem cells generate an inflammatory degenerative niche.
Ambrosi TH, Marecic O, McArdle A, Sinha R, Gulati GS, Tong X, Wang Y, Steininger HM, Hoover MY, Koepke LS, Murphy MP, Sokol J, Seo EY, Tevlin R, Lopez M, Brewer RE, Mascharak S, Lu L, Ajanaku O, Conley SD, Seita J, Morri M, Neff NF, Sahoo D, Yang F, Weissman IL, Longaker MT, Chan CKF. Ambrosi TH, et al. Nature. 2021 Sep;597(7875):256-262. doi: 10.1038/s41586-021-03795-7. Epub 2021 Aug 11. Nature. 2021. PMID: 34381212 Free PMC article.
Distinct skeletal stem cell types orchestrate long bone skeletogenesis.
Ambrosi TH, Sinha R, Steininger HM, Hoover MY, Murphy MP, Koepke LS, Wang Y, Lu WJ, Morri M, Neff NF, Weissman IL, Longaker MT, Chan CK. Ambrosi TH, et al. Elife. 2021 Jul 19;10:e66063. doi: 10.7554/eLife.66063. Elife. 2021. PMID: 34280086 Free PMC article.