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Desmosterol suppresses macrophage inflammasome activation and protects against vascular inflammation and atherosclerosis.
Zhang X, McDonald JG, Aryal B, Canfrán-Duque A, Goldberg EL, Araldi E, Ding W, Fan Y, Thompson BM, Singh AK, Li Q, Tellides G, Ordovás-Montanes J, García Milian R, Dixit VD, Ikonen E, Suárez Y, Fernández-Hernando C. Zhang X, et al. Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2107682118. doi: 10.1073/pnas.2107682118. Proc Natl Acad Sci U S A. 2021. PMID: 34782454 Free PMC article.
How Inflammation Blunts Innate Immunity in Aging.
Goldberg EL, Shaw AC, Montgomery RR. Goldberg EL, et al. Interdiscip Top Gerontol Geriatr. 2020;43:1-17. doi: 10.1159/000504480. Epub 2020 Apr 9. Interdiscip Top Gerontol Geriatr. 2020. PMID: 32294641 Free PMC article. Review.