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Mitochondrial Aging Defects Emerge in Directly Reprogrammed Human Neurons due to Their Metabolic Profile.
Kim Y, Zheng X, Ansari Z, Bunnell MC, Herdy JR, Traxler L, Lee H, Paquola ACM, Blithikioti C, Ku M, Schlachetzki JCM, Winkler J, Edenhofer F, Glass CK, Paucar AA, Jaeger BN, Pham S, Boyer L, Campbell BC, Hunter T, Mertens J, Gage FH. Kim Y, et al. Cell Rep. 2018 May 29;23(9):2550-2558. doi: 10.1016/j.celrep.2018.04.105. Cell Rep. 2018. PMID: 29847787 Free PMC article.
Human neurons to model aging: A dish best served old.
Böhnke L, Traxler L, Herdy JR, Mertens J. Böhnke L, et al. Drug Discov Today Dis Models. 2018 Spring;27:43-49. doi: 10.1016/j.ddmod.2019.01.001. Epub 2019 Feb 12. Drug Discov Today Dis Models. 2018. PMID: 31745399 Free PMC article.