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The Amygdala Noradrenergic System Is Compromised With Alcohol Use Disorder.
Varodayan FP, Patel RR, Matzeu A, Wolfe SA, Curley DE, Khom S, Gandhi PJ, Rodriguez L, Bajo M, D'Ambrosio S, Sun H, Kerr TM, Gonzales RA, Leggio L, Natividad LA, Haass-Koffler CL, Martin-Fardon R, Roberto M. Varodayan FP, et al. Biol Psychiatry. 2022 Jun 15;91(12):1008-1018. doi: 10.1016/j.biopsych.2022.02.006. Epub 2022 Apr 13. Biol Psychiatry. 2022. PMID: 35430085 Free PMC article.
Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala.
Suárez J, Khom S, Alén F, Natividad LA, Varodayan FP, Patel RR, Kirson D, Arco R, Ballesta A, Bajo M, Rubio L, Martin-Fardon R, Rodríguez de Fonseca F, Roberto M. Suárez J, et al. Addict Biol. 2020 Sep;25(5):e12813. doi: 10.1111/adb.12813. Epub 2019 Jul 24. Addict Biol. 2020. PMID: 31339221 Free PMC article.
Deficient endocannabinoid signaling in the central amygdala contributes to alcohol dependence-related anxiety-like behavior and excessive alcohol intake.
Serrano A, Pavon FJ, Buczynski MW, Schlosburg J, Natividad LA, Polis IY, Stouffer DG, Zorrilla EP, Roberto M, Cravatt BF, Martin-Fardon R, Rodriguez de Fonseca F, Parsons LH. Serrano A, et al. Neuropsychopharmacology. 2018 Aug;43(9):1840-1850. doi: 10.1038/s41386-018-0055-3. Epub 2018 Apr 5. Neuropsychopharmacology. 2018. PMID: 29748627 Free PMC article.
12 results