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2022 1
2024 3

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Page 1
Reversal of C9orf72 mutation-induced transcriptional dysregulation and pathology in cultured human neurons by allele-specific excision.
Sachdev A, Gill K, Sckaff M, Birk AM, Aladesuyi Arogundade O, Brown KA, Chouhan RS, Issagholian-Lewin PO, Patel E, Watry HL, Bernardi MT, Keough KC, Tsai YC, Smith AST, Conklin BR, Clelland CD. Sachdev A, et al. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2307814121. doi: 10.1073/pnas.2307814121. Epub 2024 Apr 15. Proc Natl Acad Sci U S A. 2024. PMID: 38621131 Free PMC article.
Validated assays for the quantification of C9orf72 human pathology.
Salomonsson SE, Maltos AM, Gill K, Aladesuyi Arogundade O, Brown KA, Sachdev A, Sckaff M, Lam KJK, Fisher IJ, Chouhan RS, Van Laar VS, Marley CB, McLaughlin I, Bankiewicz KS, Tsai YC, Conklin BR, Clelland CD. Salomonsson SE, et al. Sci Rep. 2024 Jan 8;14(1):828. doi: 10.1038/s41598-023-50667-3. Sci Rep. 2024. PMID: 38191789 Free PMC article.
Novel avenues of tau research.
Sexton CE, Bitan G, Bowles KR, Brys M, Buée L, Maina MB, Clelland CD, Cohen AD, Crary JF, Dage JL, Diaz K, Frost B, Gan L, Goate AM, Golbe LI, Hansson O, Karch CM, Kolb HC, La Joie R, Lee SE, Matallana D, Miller BL, Onyike CU, Quiroz YT, Rexach JE, Rohrer JD, Rommel A, Sadri-Vakili G, Schindler SE, Schneider JA, Sperling RA, Teunissen CE, Weninger SC, Worley SL, Zheng H, Carrillo MC. Sexton CE, et al. Alzheimers Dement. 2024 Mar;20(3):2240-2261. doi: 10.1002/alz.13533. Epub 2024 Jan 3. Alzheimers Dement. 2024. PMID: 38170841 Free PMC article. Review.
A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states.
Dräger NM, Sattler SM, Huang CT, Teter OM, Leng K, Hashemi SH, Hong J, Aviles G, Clelland CD, Zhan L, Udeochu JC, Kodama L, Singleton AB, Nalls MA, Ichida J, Ward ME, Faghri F, Gan L, Kampmann M. Dräger NM, et al. Nat Neurosci. 2022 Sep;25(9):1149-1162. doi: 10.1038/s41593-022-01131-4. Epub 2022 Aug 11. Nat Neurosci. 2022. PMID: 35953545 Free PMC article.