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Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain.
Rayaprolu S, Bitarafan S, Santiago JV, Betarbet R, Sunna S, Cheng L, Xiao H, Nelson RS, Kumar P, Bagchi P, Duong DM, Goettemoeller AM, Oláh VJ, Rowan M, Levey AI, Wood LB, Seyfried NT, Rangaraju S. Rayaprolu S, et al. Nat Commun. 2022 May 25;13(1):2927. doi: 10.1038/s41467-022-30623-x. Nat Commun. 2022. PMID: 35614064 Free PMC article.
Unique molecular characteristics and microglial origin of Kv1.3 channel-positive brain myeloid cells in Alzheimer's disease.
Ramesha S, Rayaprolu S, Bowen CA, Giver CR, Bitarafan S, Nguyen HM, Gao T, Chen MJ, Nwabueze N, Dammer EB, Engstrom AK, Xiao H, Pennati A, Seyfried NT, Katz DJ, Galipeau J, Wulff H, Waller EK, Wood LB, Levey AI, Rangaraju S. Ramesha S, et al. Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):e2013545118. doi: 10.1073/pnas.2013545118. Proc Natl Acad Sci U S A. 2021. PMID: 33649184 Free PMC article.
Kv1.3 modulates neuroinflammation and neurodegeneration in Parkinson's disease.
Sarkar S, Nguyen HM, Malovic E, Luo J, Langley M, Palanisamy BN, Singh N, Manne S, Neal M, Gabrielle M, Abdalla A, Anantharam P, Rokad D, Panicker N, Singh V, Ay M, Charli A, Harischandra D, Jin LW, Jin H, Rangaraju S, Anantharam V, Wulff H, Kanthasamy AG. Sarkar S, et al. J Clin Invest. 2020 Aug 3;130(8):4195-4212. doi: 10.1172/JCI136174. J Clin Invest. 2020. PMID: 32597830 Free PMC article.
Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer's disease.
Rayaprolu S, Gao T, Xiao H, Ramesha S, Weinstock LD, Shah J, Duong DM, Dammer EB, Webster JA Jr, Lah JJ, Wood LB, Betarbet R, Levey AI, Seyfried NT, Rangaraju S. Rayaprolu S, et al. Mol Neurodegener. 2020 May 7;15(1):28. doi: 10.1186/s13024-020-00377-5. Mol Neurodegener. 2020. PMID: 32381088 Free PMC article.
21 results