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Thalamic and prefrontal GABA concentrations but not GABAA receptor densities are altered in high-functioning adults with autism spectrum disorder.
Fung LK, Flores RE, Gu M, Sun KL, James D, Schuck RK, Jo B, Park JH, Lee BC, Jung JH, Kim SE, Saggar M, Sacchet MD, Warnock G, Khalighi MM, Spielman D, Chin FT, Hardan AY. Fung LK, et al. Mol Psychiatry. 2021 May;26(5):1634-1646. doi: 10.1038/s41380-020-0756-y. Epub 2020 May 6. Mol Psychiatry. 2021. PMID: 32376999 Free PMC article.
A randomized placebo-controlled pilot trial shows that intranasal vasopressin improves social deficits in children with autism.
Parker KJ, Oztan O, Libove RA, Mohsin N, Karhson DS, Sumiyoshi RD, Summers JE, Hinman KE, Motonaga KS, Phillips JM, Carson DS, Fung LK, Garner JP, Hardan AY. Parker KJ, et al. Sci Transl Med. 2019 May 8;11(491):eaau7356. doi: 10.1126/scitranslmed.aau7356. Epub 2019 May 1. Sci Transl Med. 2019. PMID: 31043522 Free PMC article. Clinical Trial.