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Phase II clinical trial of metformin as a cancer stem cell-targeting agent in ovarian cancer.
Brown JR, Chan DK, Shank JJ, Griffith KA, Fan H, Szulawski R, Yang K, Reynolds RK, Johnston C, McLean K, Uppal S, Liu JR, Cabrera L, Taylor SE, Orr BC, Modugno F, Mehta P, Bregenzer M, Mehta G, Shen H, Coffman LG, Buckanovich RJ. Brown JR, et al. JCI Insight. 2020 Jun 4;5(11):e133247. doi: 10.1172/jci.insight.133247. JCI Insight. 2020. PMID: 32369446 Free PMC article. Clinical Trial.
The double edge sword of fibrosis in cancer.
Chandler C, Liu T, Buckanovich R, Coffman LG. Chandler C, et al. Transl Res. 2019 Jul;209:55-67. doi: 10.1016/j.trsl.2019.02.006. Epub 2019 Feb 21. Transl Res. 2019. PMID: 30871956 Free PMC article. Review.