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2018 | 1 |
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Gold(I) ion and the phosphine ligand are necessary for the anti-Toxoplasma gondii activity of auranofin.
Microbiol Spectr. 2024 Feb 6;12(2):e0296823. doi: 10.1128/spectrum.02968-23. Epub 2024 Jan 11.
Microbiol Spectr. 2024.
PMID: 38206030
Free PMC article.
Auranofin Resistance in Toxoplasma gondii Decreases the Accumulation of Reactive Oxygen Species but Does Not Target Parasite Thioredoxin Reductase.
Ma CI, Tirtorahardjo JA, Jan S, Schweizer SS, Rosario SAC, Du Y, Zhang JJ, Morrissette NS, Andrade RM.
Ma CI, et al.
Front Cell Infect Microbiol. 2021 Mar 19;11:618994. doi: 10.3389/fcimb.2021.618994. eCollection 2021.
Front Cell Infect Microbiol. 2021.
PMID: 33816332
Free PMC article.
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Two key cathepsins, TgCPB and TgCPL, are targeted by the vinyl sulfone inhibitor K11777 in in vitro and in vivo models of toxoplasmosis.
Chaparro JD, Cheng T, Tran UP, Andrade RM, Brenner SBT, Hwang G, Cohn S, Hirata K, McKerrow JH, Reed SL.
Chaparro JD, et al.
PLoS One. 2018 Mar 22;13(3):e0193982. doi: 10.1371/journal.pone.0193982. eCollection 2018.
PLoS One. 2018.
PMID: 29565998
Free PMC article.
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New drug target in protozoan parasites: the role of thioredoxin reductase.
Andrade RM, Reed SL.
Andrade RM, et al.
Front Microbiol. 2015 Sep 30;6:975. doi: 10.3389/fmicb.2015.00975. eCollection 2015.
Front Microbiol. 2015.
PMID: 26483758
Free PMC article.
Review.
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