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Page 1
Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation.
Liu TC, Kern JT, Jain U, Sonnek NM, Xiong S, Simpson KF, VanDussen KL, Winkler ES, Haritunians T, Malique A, Lu Q, Sasaki Y, Storer C, Diamond MS, Head RD, McGovern DPB, Stappenbeck TS. Liu TC, et al. Cell Host Microbe. 2021 Jun 9;29(6):988-1001.e6. doi: 10.1016/j.chom.2021.04.004. Epub 2021 May 18. Cell Host Microbe. 2021. PMID: 34010595 Free PMC article.
Epithelial Cell Biomarkers Are Predictive of Response to Biologic Agents in Crohn's Disease.
Osterman MT, VanDussen KL, Gordon IO, Davis EM, Li K, Simpson K, Ciorba M, Glover SC, Abraham B, Guo X, Yee EU, Allard FD, Perrigoue JG, Claggett B, Shen B, Stappenbeck TS, Liu JJ. Osterman MT, et al. Inflamm Bowel Dis. 2021 Apr 15;27(5):677-685. doi: 10.1093/ibd/izaa251. Inflamm Bowel Dis. 2021. PMID: 32964238 Free PMC article. Clinical Trial.
Patient-derived small intestinal myofibroblasts direct perfused, physiologically responsive capillary development in a microfluidic Gut-on-a-Chip Model.
Seiler KM, Bajinting A, Alvarado DM, Traore MA, Binkley MM, Goo WH, Lanik WE, Ou J, Ismail U, Iticovici M, King CR, VanDussen KL, Swietlicki EA, Gazit V, Guo J, Luke CJ, Stappenbeck T, Ciorba MA, George SC, Meacham JM, Rubin DC, Good M, Warner BW. Seiler KM, et al. Sci Rep. 2020 Mar 2;10(1):3842. doi: 10.1038/s41598-020-60672-5. Sci Rep. 2020. PMID: 32123209 Free PMC article.
Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells.
Wang Y, Chiang IL, Ohara TE, Fujii S, Cheng J, Muegge BD, Ver Heul A, Han ND, Lu Q, Xiong S, Chen F, Lai CW, Janova H, Wu R, Whitehurst CE, VanDussen KL, Liu TC, Gordon JI, Sibley LD, Stappenbeck TS. Wang Y, et al. Cell. 2019 Nov 14;179(5):1144-1159.e15. doi: 10.1016/j.cell.2019.10.015. Epub 2019 Nov 7. Cell. 2019. PMID: 31708126 Free PMC article.
Epithelial Indoleamine 2,3-Dioxygenase 1 Modulates Aryl Hydrocarbon Receptor and Notch Signaling to Increase Differentiation of Secretory Cells and Alter Mucus-Associated Microbiota.
Alvarado DM, Chen B, Iticovici M, Thaker AI, Dai N, VanDussen KL, Shaikh N, Lim CK, Guillemin GJ, Tarr PI, Ciorba MA. Alvarado DM, et al. Gastroenterology. 2019 Oct;157(4):1093-1108.e11. doi: 10.1053/j.gastro.2019.07.013. Epub 2019 Jul 17. Gastroenterology. 2019. PMID: 31325428 Free PMC article.
A Stem-Cell-Derived Platform Enables Complete Cryptosporidium Development In Vitro and Genetic Tractability.
Wilke G, Funkhouser-Jones LJ, Wang Y, Ravindran S, Wang Q, Beatty WL, Baldridge MT, VanDussen KL, Shen B, Kuhlenschmidt MS, Kuhlenschmidt TB, Witola WH, Stappenbeck TS, Sibley LD. Wilke G, et al. Cell Host Microbe. 2019 Jul 10;26(1):123-134.e8. doi: 10.1016/j.chom.2019.05.007. Epub 2019 Jun 20. Cell Host Microbe. 2019. PMID: 31231046 Free PMC article.
18 results