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SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemia.
Johansson P, Klein-Hitpass L, Choidas A, Habenberger P, Mahboubi B, Kim B, Bergmann A, Scholtysik R, Brauser M, Lollies A, Siebert R, Zenz T, Dührsen U, Küppers R, Dürig J. Johansson P, et al. Among authors: kuppers r. Blood Cancer J. 2018 Jan 19;8(1):11. doi: 10.1038/s41408-017-0036-5. Blood Cancer J. 2018. PMID: 29352181 Free PMC article. Clinical Trial.
Molecular analysis of single B cells from T-cell-rich B-cell lymphoma shows the derivation of the tumor cells from mutating germinal center B cells and exemplifies means by which immunoglobulin genes are modified in germinal center B cells.
Bräuninger A, Küppers R, Spieker T, Siebert R, Strickler JG, Schlegelberger B, Rajewsky K, Hansmann ML. Bräuninger A, et al. Among authors: kuppers r. Blood. 1999 Apr 15;93(8):2679-87. Blood. 1999. PMID: 10194448 Free article.
Chromosomal breakpoints affecting immunoglobulin loci are recurrent in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma.
Martín-Subero JI, Klapper W, Sotnikova A, Callet-Bauchu E, Harder L, Bastard C, Schmitz R, Grohmann S, Höppner J, Riemke J, Barth TF, Berger F, Bernd HW, Claviez A, Gesk S, Frank GA, Kaplanskaya IB, Möller P, Parwaresch RM, Rüdiger T, Stein H, Küppers R, Hansmann ML, Siebert R; Deutsche Krebshilfe Network Project Molecular Mechanisms in Malignant Lymphomas. Martín-Subero JI, et al. Among authors: kuppers r. Cancer Res. 2006 Nov 1;66(21):10332-8. doi: 10.1158/0008-5472.CAN-06-1992. Cancer Res. 2006. PMID: 17079453
A comprehensive genetic and histopathologic analysis identifies two subgroups of B-cell malignancies carrying a t(14;19)(q32;q13) or variant BCL3-translocation.
Martín-Subero JI, Ibbotson R, Klapper W, Michaux L, Callet-Bauchu E, Berger F, Calasanz MJ, De Wolf-Peeters C, Dyer MJ, Felman P, Gardiner A, Gascoyne RD, Gesk S, Harder L, Horsman DE, Kneba M, Küppers R, Majid A, Parry-Jones N, Ritgen M, Salido M, Solé F, Thiel G, Wacker HH, Oscier D, Wlodarska I, Siebert R. Martín-Subero JI, et al. Among authors: kuppers r. Leukemia. 2007 Jul;21(7):1532-44. doi: 10.1038/sj.leu.2404695. Epub 2007 May 10. Leukemia. 2007. PMID: 17495977
Identification of candidate tumour suppressor gene loci for Hodgkin and Reed-Sternberg cells by characterisation of homozygous deletions in classical Hodgkin lymphoma cell lines.
Giefing M, Arnemann J, Martin-Subero JI, Nieländer I, Bug S, Hartmann S, Arnold N, Tiacci E, Frank M, Hansmann ML, Küppers R, Siebert R. Giefing M, et al. Among authors: kuppers r. Br J Haematol. 2008 Sep;142(6):916-24. doi: 10.1111/j.1365-2141.2008.07262.x. Epub 2008 Jul 30. Br J Haematol. 2008. PMID: 18671701 Free article.
BCL2 and BCL3 are recurrent translocation partners of the IGH locus.
Szymanowska N, Klapper W, Gesk S, Küppers R, Martín-Subero JI, Siebert R. Szymanowska N, et al. Among authors: kuppers r. Cancer Genet Cytogenet. 2008 Oct 15;186(2):110-4. doi: 10.1016/j.cancergencyto.2008.06.007. Cancer Genet Cytogenet. 2008. PMID: 18940474
371 results