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Lack of CCDC146, a ubiquitous centriole and microtubule-associated protein, leads to non-syndromic male infertility in human and mouse.
Muroňová J, Kherraf ZE, Giordani E, Lambert E, Eckert S, Cazin C, Amiri-Yekta A, Court M, Chevalier G, Martinez G, Neirijnck Y, Kühne F, Wehrli L, Klena N, Hamel V, De Macedo L, Escoffier J, Guichard P, Coutton C, Mustapha SFB, Kharouf M, Bouin AP, Zouari R, Thierry-Mieg N, Nef S, Geimer S, Loeuillet C, Ray PF, Arnoult C. Muroňová J, et al. Among authors: kuhne f. Elife. 2024 Mar 5;12:RP86845. doi: 10.7554/eLife.86845. Elife. 2024. PMID: 38441556 Free PMC article.
Combined Use of Whole Exome Sequencing and CRISPR/Cas9 to Study the Etiology of Non-Obstructive Azoospermia: Demonstration of the Dispensable Role of the Testis-Specific Genes C1orf185 and CCT6B.
Cazin C, Neirijnck Y, Loeuillet C, Wehrli L, Kühne F, Lordey I, Mustapha SFB, Bouker A, Zouari R, Thierry-Mieg N, Nef S, Arnoult C, Ray PF, Kherraf ZE. Cazin C, et al. Among authors: kuhne f. Cells. 2021 Dec 30;11(1):118. doi: 10.3390/cells11010118. Cells. 2021. PMID: 35011680 Free PMC article.
Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cells.
Neirijnck Y, Calvel P, Kilcoyne KR, Kühne F, Stévant I, Griffeth RJ, Pitetti JL, Andric SA, Hu MC, Pralong F, Smith LB, Nef S. Neirijnck Y, et al. Among authors: kuhne f. FASEB J. 2018 Jun;32(6):3321-3335. doi: 10.1096/fj.201700769RR. Epub 2018 Jan 24. FASEB J. 2018. PMID: 29401624
Taken together, these data reveal the cell-autonomous and nonautonomous roles of the IGF system for proper development and maintenance of steroidogenic lineages.-Neirijnck, Y., Calvel, P., Kilcoyne, K. R., Kuhne, F., Stevant, I., Griffeth, R. J., Pitetti, J.-L., And …
Taken together, these data reveal the cell-autonomous and nonautonomous roles of the IGF system for proper development and maintenance of st …
Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad.
Mayère C, Regard V, Perea-Gomez A, Bunce C, Neirijnck Y, Djari C, Bellido-Carreras N, Sararols P, Reeves R, Greenaway S, Simon M, Siggers P, Condrea D, Kühne F, Gantar I, Tang F, Stévant I, Batti L, Ghyselinck NB, Wilhelm D, Greenfield A, Capel B, Chaboissier MC, Nef S. Mayère C, et al. Among authors: kuhne f. Sci Adv. 2022 May 27;8(21):eabm0972. doi: 10.1126/sciadv.abm0972. Epub 2022 May 25. Sci Adv. 2022. PMID: 35613264 Free PMC article.
143 results