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High expression of Sterol-O-Acyl transferase 1 (SOAT1), an enzyme involved in cholesterol metabolism, is associated with earlier biochemical recurrence in high risk prostate cancer.
Eckhardt C, Sbiera I, Krebs M, Sbiera S, Spahn M, Kneitz B, Joniau S, Fassnacht M, Kübler H, Weigand I, Kroiss M. Eckhardt C, et al. Among authors: kubler h. Prostate Cancer Prostatic Dis. 2022 Sep;25(3):484-490. doi: 10.1038/s41391-021-00431-3. Epub 2021 Jul 29. Prostate Cancer Prostatic Dis. 2022. PMID: 34326474 Free PMC article.
MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer.
Kalogirou C, Linxweiler J, Schmucker P, Snaebjornsson MT, Schmitz W, Wach S, Krebs M, Hartmann E, Puhr M, Müller A, Spahn M, Seitz AK, Frank T, Marouf H, Büchel G, Eckstein M, Kübler H, Eilers M, Saar M, Junker K, Röhrig F, Kneitz B, Rosenfeldt MT, Schulze A. Kalogirou C, et al. Among authors: kubler h. Nat Commun. 2021 Aug 20;12(1):5066. doi: 10.1038/s41467-021-25325-9. Nat Commun. 2021. PMID: 34417456 Free PMC article.
68Ga-PSMA I&T PET/CT for primary staging of prostate cancer.
Cytawa W, Seitz AK, Kircher S, Fukushima K, Tran-Gia J, Schirbel A, Bandurski T, Lass P, Krebs M, Połom W, Matuszewski M, Wester HJ, Buck AK, Kübler H, Lapa C. Cytawa W, et al. Among authors: kubler h. Eur J Nucl Med Mol Imaging. 2020 Jan;47(1):168-177. doi: 10.1007/s00259-019-04524-z. Epub 2019 Sep 16. Eur J Nucl Med Mol Imaging. 2020. PMID: 31529265
miR-221 Augments TRAIL-Mediated Apoptosis in Prostate Cancer Cells by Inducing Endogenous TRAIL Expression and Targeting the Functional Repressors SOCS3 and PIK3R1.
Krebs M, Behrmann C, Kalogirou C, Sokolakis I, Kneitz S, Kruithof-de Julio M, Zoni E, Rech A, Schilling B, Kübler H, Spahn M, Kneitz B. Krebs M, et al. Among authors: kubler h. Biomed Res Int. 2019 Nov 14;2019:6392748. doi: 10.1155/2019/6392748. eCollection 2019. Biomed Res Int. 2019. PMID: 31828111 Free PMC article.
KLK3 and TMPRSS2 for molecular lymph-node staging in prostate cancer patients undergoing radical prostatectomy.
Lunger L, Retz M, Bandur M, Souchay M, Vitzthum E, Jäger M, Weirich G, Schuster T, Autenrieth M, Kübler H, Maurer T, Thalgott M, Herkommer K, Koll F, Gschwend JE, Nawroth R, Heck MM. Lunger L, et al. Among authors: kubler h. Prostate Cancer Prostatic Dis. 2021 Jun;24(2):362-369. doi: 10.1038/s41391-020-00283-3. Epub 2020 Sep 25. Prostate Cancer Prostatic Dis. 2021. PMID: 32978525 Free PMC article.
Usability and diagnostic accuracy of different MRI/ultrasound-guided fusion biopsy systems for the detection of clinically significant and insignificant prostate cancer: a prospective cohort study.
Sokolakis I, Pyrgidis N, Koneval L, Krebs M, Thurner A, Kübler H, Hatzichristodoulou G. Sokolakis I, et al. Among authors: kubler h. World J Urol. 2021 Nov;39(11):4101-4108. doi: 10.1007/s00345-021-03761-y. Epub 2021 Jun 17. World J Urol. 2021. PMID: 34142231
164 results