König S - Search Results

1

Gliotoxin from Aspergillus fumigatus Abrogates Leukotriene B₄ Formation through Inhibition of Leukotriene A₄ Hydrolase.

König S, Pace S, Pein H, Heinekamp T, Kramer J, Romp E, Straßburger M, Troisi F, Proschak A, Dworschak J, Scherlach K, Rossi A, Sautebin L, Haeggström JZ, Hertweck C, Brakhage AA, Gerstmeier J, Proschak E, Werz O. König S, et al. Cell Chem Biol. 2019 Apr 18;26(4):524-534.e5. doi: 10.1016/j.chembiol.2019.01.001. Epub 2019 Feb 7. Cell Chem Biol. 2019. PMID: 30745237 Free article.

2

Indirubin core structure of glycogen synthase kinase-3 inhibitors as novel chemotype for intervention with 5-lipoxygenase.

Pergola C, Gaboriaud-Kolar N, Jestädt N, König S, Kritsanida M, Schaible AM, Li H, Garscha U, Weinigel C, Barz D, Albring KF, Huber O, Skaltsounis AL, Werz O. Pergola C, et al. Among authors: konig s. J Med Chem. 2014 May 8;57(9):3715-23. doi: 10.1021/jm401740w. Epub 2014 Apr 17. J Med Chem. 2014. PMID: 24697244

3

Melleolides induce rapid cell death in human primary monocytes and cancer cells.

Bohnert M, Scherer O, Wiechmann K, König S, Dahse HM, Hoffmeister D, Werz O. Bohnert M, et al. Among authors: konig s. Bioorg Med Chem. 2014 Aug 1;22(15):3856-61. doi: 10.1016/j.bmc.2014.06.032. Epub 2014 Jun 25. Bioorg Med Chem. 2014. PMID: 25028062

4

Structure and biosynthetic assembly of gulmirecins, macrolide antibiotics from the predatory bacterium Pyxidicoccus fallax.

Schieferdecker S, König S, Weigel C, Dahse HM, Werz O, Nett M. Schieferdecker S, et al. Among authors: konig s. Chemistry. 2014 Nov 24;20(48):15933-40. doi: 10.1002/chem.201404291. Epub 2014 Oct 6. Chemistry. 2014. PMID: 25287056

5

Myxochelins target human 5-lipoxygenase.

Schieferdecker S, König S, Koeberle A, Dahse HM, Werz O, Nett M. Schieferdecker S, et al. Among authors: konig s. J Nat Prod. 2015 Feb 27;78(2):335-8. doi: 10.1021/np500909b. Epub 2015 Feb 16. J Nat Prod. 2015. PMID: 25686392

6

Harnessing Enzymatic Promiscuity in Myxochelin Biosynthesis for the Production of 5-Lipoxygenase Inhibitors.

Korp J, König S, Schieferdecker S, Dahse HM, König GM, Werz O, Nett M. Korp J, et al. Among authors: konig gm, konig s. Chembiochem. 2015 Nov;16(17):2445-50. doi: 10.1002/cbic.201500446. Epub 2015 Oct 13. Chembiochem. 2015. PMID: 26416255

7

Myxochelin-Inspired 5-Lipoxygenase Inhibitors: Synthesis and Biological Evaluation.

Schieferdecker S, König S, Pace S, Werz O, Nett M. Schieferdecker S, et al. Among authors: konig s. ChemMedChem. 2017 Jan 5;12(1):23-27. doi: 10.1002/cmdc.201600536. Epub 2016 Nov 29. ChemMedChem. 2017. PMID: 27875023

8

Mitochondrial Chaperonin HSP60 Is the Apoptosis-Related Target for Myrtucommulone.

Wiechmann K, Müller H, König S, Wielsch N, Svatoš A, Jauch J, Werz O. Wiechmann K, et al. Among authors: konig s. Cell Chem Biol. 2017 May 18;24(5):614-623.e6. doi: 10.1016/j.chembiol.2017.04.008. Epub 2017 Apr 28. Cell Chem Biol. 2017. PMID: 28457707 Free article.

9

Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase.

Garscha U, Romp E, Pace S, Rossi A, Temml V, Schuster D, König S, Gerstmeier J, Liening S, Werner M, Atze H, Wittmann S, Weinigel C, Rummler S, Scriba GK, Sautebin L, Werz O. Garscha U, et al. Among authors: konig s. Sci Rep. 2017 Aug 24;7(1):9398. doi: 10.1038/s41598-017-09795-w. Sci Rep. 2017. PMID: 28839250 Free PMC article.

10

Triterpene Acids from Frankincense and Semi-Synthetic Derivatives That Inhibit 5-Lipoxygenase and Cathepsin G.

Koeberle A, Henkel A, Verhoff M, Tausch L, König S, Fischer D, Kather N, Seitz S, Paul M, Jauch J, Werz O. Koeberle A, et al. Among authors: konig s. Molecules. 2018 Feb 24;23(2):506. doi: 10.3390/molecules23020506. Molecules. 2018. PMID: 29495286 Free PMC article.

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