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An intact gut microbiome protects genetically predisposed mice against leukemia.
Vicente-Dueñas C, Janssen S, Oldenburg M, Auer F, González-Herrero I, Casado-García A, Isidro-Hernández M, Raboso-Gallego J, Westhoff P, Pandyra AA, Hein D, Gössling KL, Alonso-López D, De Las Rivas J, Bhatia S, García-Criado FJ, García-Cenador MB, Weber APM, Köhrer K, Hauer J, Fischer U, Sánchez-García I, Borkhardt A. Vicente-Dueñas C, et al. Among authors: kohrer k. Blood. 2020 Oct 29;136(18):2003-2017. doi: 10.1182/blood.2019004381. Blood. 2020. PMID: 32911536 Free PMC article.
Type I interferon protects antiviral CD8+ T cells from NK cell cytotoxicity.
Xu HC, Grusdat M, Pandyra AA, Polz R, Huang J, Sharma P, Deenen R, Köhrer K, Rahbar R, Diefenbach A, Gibbert K, Löhning M, Höcker L, Waibler Z, Häussinger D, Mak TW, Ohashi PS, Lang KS, Lang PA. Xu HC, et al. Among authors: kohrer k. Immunity. 2014 Jun 19;40(6):949-60. doi: 10.1016/j.immuni.2014.05.004. Epub 2014 Jun 5. Immunity. 2014. PMID: 24909887 Free article.
The Mycotoxin Beauvericin Exhibits Immunostimulatory Effects on Dendritic Cells via Activating the TLR4 Signaling Pathway.
Yang X, Ali S, Zhao M, Richter L, Schäfer V, Schliehe-Diecks J, Frank M, Qi J, Larsen PK, Skerra J, Islam H, Wachtmeister T, Alter C, Huang A, Bhatia S, Köhrer K, Kirschning C, Weighardt H, Kalinke U, Kalscheuer R, Uhrberg M, Scheu S. Yang X, et al. Among authors: kohrer k. Front Immunol. 2022 Apr 8;13:856230. doi: 10.3389/fimmu.2022.856230. eCollection 2022. Front Immunol. 2022. PMID: 35464417 Free PMC article.
Stromal alterations in patients with MGUS, smoldering myeloma and multiple myeloma.
Bogun L, Koch A, Scherer B, Fenk R, Maus U, Bormann F, Köhrer K, Petzsch P, Wachtmeister T, Zukovs R, Dietrich S, Haas R, Schroeder T, Jäger PS, Geyh S. Bogun L, et al. Among authors: kohrer k. Blood Adv. 2024 Jan 19:bloodadvances.2023011632. doi: 10.1182/bloodadvances.2023011632. Online ahead of print. Blood Adv. 2024. PMID: 38241490
Loss-of-function mutations within the IL-2 inducible kinase ITK in patients with EBV-associated lymphoproliferative diseases.
Linka RM, Risse SL, Bienemann K, Werner M, Linka Y, Krux F, Synaeve C, Deenen R, Ginzel S, Dvorsky R, Gombert M, Halenius A, Hartig R, Helminen M, Fischer A, Stepensky P, Vettenranta K, Köhrer K, Ahmadian MR, Laws HJ, Fleckenstein B, Jumaa H, Latour S, Schraven B, Borkhardt A. Linka RM, et al. Among authors: kohrer k. Leukemia. 2012 May;26(5):963-71. doi: 10.1038/leu.2011.371. Epub 2012 Jan 6. Leukemia. 2012. PMID: 22289921
Acute myeloid leukemia-induced functional inhibition of healthy CD34+ hematopoietic stem and progenitor cells.
Jäger P, Geyh S, Twarock S, Cadeddu RP, Rabes P, Koch A, Maus U, Hesper T, Zilkens C, Rautenberg C, Bormann F, Köhrer K, Petzsch P, Wieczorek D, Betz B, Surowy H, Hildebrandt B, Germing U, Kobbe G, Haas R, Schroeder T. Jäger P, et al. Among authors: kohrer k. Stem Cells. 2021 Sep;39(9):1270-1284. doi: 10.1002/stem.3387. Epub 2021 May 20. Stem Cells. 2021. PMID: 34013984
Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease.
Lang J, Bohn P, Bhat H, Jastrow H, Walkenfort B, Cansiz F, Fink J, Bauer M, Olszewski D, Ramos-Nascimento A, Duhan V, Friedrich SK, Becker KA, Krawczyk A, Edwards MJ, Burchert A, Huber M, Friebus-Kardash J, Göthert JR, Hardt C, Probst HC, Schumacher F, Köhrer K, Kleuser B, Babiychuk EB, Sodeik B, Seibel J, Greber UF, Lang PA, Gulbins E, Lang KS. Lang J, et al. Among authors: kohrer k. Nat Commun. 2020 Mar 12;11(1):1338. doi: 10.1038/s41467-020-15072-8. Nat Commun. 2020. PMID: 32165633 Free PMC article.
172 results