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Potent dual MAGL/FAAH inhibitor AKU-005 engages endocannabinoids to diminish meningeal nociception implicated in migraine pain.
Della Pietra A, Krivoshein G, Ivanov K, Giniatullina R, Jyrkkänen HK, Leinonen V, Lehtonen M, van den Maagdenberg AMJM, Savinainen J, Giniatullin R. Della Pietra A, et al. Among authors: jyrkkanen hk. J Headache Pain. 2023 Apr 11;24(1):38. doi: 10.1186/s10194-023-01568-3. J Headache Pain. 2023. PMID: 37038131 Free PMC article.
Psychiatric disorders are a common prognostic marker for worse outcome in patients with idiopathic intracranial hypertension.
Puustinen T, Tervonen J, Avellan C, Jyrkkänen HK, Paterno JJ, Hartikainen P, Vanhanen U, Leinonen V, Lehto SM, Elomaa AP, Huttunen TJ. Puustinen T, et al. Among authors: jyrkkanen hk. Clin Neurol Neurosurg. 2019 Nov;186:105527. doi: 10.1016/j.clineuro.2019.105527. Epub 2019 Sep 17. Clin Neurol Neurosurg. 2019. PMID: 31586855 Free article.
Surgically Treated C1 Fractures: A Population-Based Study.
Ylönen H, Danner N, Jyrkkänen HK, Kämäräinen OP, Leinonen V, Huttunen J. Ylönen H, et al. Among authors: jyrkkanen hk. World Neurosurg. 2021 Oct;154:e333-e342. doi: 10.1016/j.wneu.2021.07.046. Epub 2021 Jul 17. World Neurosurg. 2021. PMID: 34284160 Free article.
Cerebrospinal fluid dynamics in idiopathic intracranial hypertension: a literature review and validation of contemporary findings.
Kaipainen AL, Martoma E, Puustinen T, Tervonen J, Jyrkkänen HK, Paterno JJ, Kotkansalo A, Rantala S, Vanhanen U, Leinonen V, Lehto SM, Iso-Mustajärvi M, Elomaa AP, Qvarlander S, Huuskonen TJ. Kaipainen AL, et al. Among authors: jyrkkanen hk. Acta Neurochir (Wien). 2021 Dec;163(12):3353-3368. doi: 10.1007/s00701-021-04940-x. Epub 2021 Aug 27. Acta Neurochir (Wien). 2021. PMID: 34453214 Free PMC article. Review.
Incidence and risk factors of spinal cord stimulation for persistent or recurrent pain after lumbar spine surgery: a population-based study.
Huttunen J, Fraunberg MVUZ, Ikäheimo TM, Jyrkkänen HK, Nissen M, Leinonen V, Salmenkivi J, Malmivaara A, Sirola J, Sund R. Huttunen J, et al. Among authors: jyrkkanen hk. Acta Neurochir (Wien). 2022 Oct;164(10):2645-2653. doi: 10.1007/s00701-022-05268-w. Epub 2022 Jun 17. Acta Neurochir (Wien). 2022. PMID: 35713719 Free PMC article.
In vivo assessment of Lewy body and beta-amyloid copathologies in idiopathic normal pressure hydrocephalus: prevalence and associations with clinical features and surgery outcome.
Giannini G, Baiardi S, Dellavalle S, Zenesini C, Cevoli S, Danner N, Jyrkkänen HK, Rossi M, Polischi B, Quadalti C, Stefanini C, Cortelli P, Milletti D, Herukka SK, Palandri G, Leinonen V, Parchi P. Giannini G, et al. Among authors: jyrkkanen hk. Fluids Barriers CNS. 2022 Sep 7;19(1):71. doi: 10.1186/s12987-022-00368-2. Fluids Barriers CNS. 2022. PMID: 36071460 Free PMC article.
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