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Exposure to environmental contaminants is associated with altered hepatic lipid metabolism in non-alcoholic fatty liver disease.
Sen P, Qadri S, Luukkonen PK, Ragnarsdottir O, McGlinchey A, Jäntti S, Juuti A, Arola J, Schlezinger JJ, Webster TF, Orešič M, Yki-Järvinen H, Hyötyläinen T. Sen P, et al. Among authors: juuti a. J Hepatol. 2022 Feb;76(2):283-293. doi: 10.1016/j.jhep.2021.09.039. Epub 2021 Oct 7. J Hepatol. 2022. PMID: 34627976 Free article.
Prediction of non-alcoholic fatty-liver disease and liver fat content by serum molecular lipids.
Orešič M, Hyötyläinen T, Kotronen A, Gopalacharyulu P, Nygren H, Arola J, Castillo S, Mattila I, Hakkarainen A, Borra RJ, Honka MJ, Verrijken A, Francque S, Iozzo P, Leivonen M, Jaser N, Juuti A, Sørensen TI, Nuutila P, Van Gaal L, Yki-Järvinen H. Orešič M, et al. Among authors: juuti a. Diabetologia. 2013 Oct;56(10):2266-74. doi: 10.1007/s00125-013-2981-2. Epub 2013 Jul 4. Diabetologia. 2013. PMID: 23824212 Free PMC article.
A population-based study on the prevalence of NASH using scores validated against liver histology.
Hyysalo J, Männistö VT, Zhou Y, Arola J, Kärjä V, Leivonen M, Juuti A, Jaser N, Lallukka S, Käkelä P, Venesmaa S, Simonen M, Saltevo J, Moilanen L, Korpi-Hyövalti E, Keinänen-Kiukaanniemi S, Oksa H, Orho-Melander M, Valenti L, Fargion S, Pihlajamäki J, Peltonen M, Yki-Järvinen H. Hyysalo J, et al. Among authors: juuti a. J Hepatol. 2014 Apr;60(4):839-46. doi: 10.1016/j.jhep.2013.12.009. Epub 2013 Dec 12. J Hepatol. 2014. PMID: 24333862
Impaired hepatic lipid synthesis from polyunsaturated fatty acids in TM6SF2 E167K variant carriers with NAFLD.
Luukkonen PK, Zhou Y, Nidhina Haridas PA, Dwivedi OP, Hyötyläinen T, Ali A, Juuti A, Leivonen M, Tukiainen T, Ahonen L, Scott E, Palmer JM, Arola J, Orho-Melander M, Vikman P, Anstee QM, Olkkonen VM, Orešič M, Groop L, Yki-Järvinen H. Luukkonen PK, et al. Among authors: juuti a. J Hepatol. 2017 Jul;67(1):128-136. doi: 10.1016/j.jhep.2017.02.014. Epub 2017 Feb 22. J Hepatol. 2017. PMID: 28235613
Hydroxysteroid 17-β dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver disease.
Luukkonen PK, Tukiainen T, Juuti A, Sammalkorpi H, Haridas PAN, Niemelä O, Arola J, Orho-Melander M, Hakkarainen A, Kovanen PT, Dwivedi O, Groop L, Hodson L, Gastaldelli A, Hyötyläinen T, Orešič M, Yki-Järvinen H. Luukkonen PK, et al. Among authors: juuti a. JCI Insight. 2020 Mar 12;5(5):e132158. doi: 10.1172/jci.insight.132158. JCI Insight. 2020. PMID: 32161197 Free PMC article.
The PNPLA3-I148M variant increases polyunsaturated triglycerides in human adipose tissue.
Qadri S, Lallukka-Brück S, Luukkonen PK, Zhou Y, Gastaldelli A, Orho-Melander M, Sammalkorpi H, Juuti A, Penttilä AK, Perttilä J, Hakkarainen A, Lehtimäki TE, Orešič M, Hyötyläinen T, Hodson L, Olkkonen VM, Yki-Järvinen H. Qadri S, et al. Among authors: juuti a. Liver Int. 2020 Sep;40(9):2128-2138. doi: 10.1111/liv.14507. Epub 2020 May 18. Liver Int. 2020. PMID: 32386450
60 results