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528 results

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Page 1
Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry.
Darst BF, Shen J, Madduri RK, Rodriguez AA, Xiao Y, Sheng X, Saunders EJ, Dadaev T, Brook MN, Hoffmann TJ, Muir K, Wan P, Le Marchand L, Wilkens L, Wang Y, Schleutker J, MacInnis RJ, Cybulski C, Neal DE, Nordestgaard BG, Nielsen SF, Batra J, Clements JA; Australian Prostate Cancer BioResource; Grönberg H, Pashayan N, Travis RC, Park JY, Albanes D, Weinstein S, Mucci LA, Hunter DJ, Penney KL, Tangen CM, Hamilton RJ, Parent MÉ, Stanford JL, Koutros S, Wolk A, Sørensen KD, Blot WJ, Yeboah ED, Mensah JE, Lu YJ, Schaid DJ, Thibodeau SN, West CM, Maier C, Kibel AS, Cancel-Tassin G, Menegaux F, John EM, Grindedal EM, Khaw KT, Ingles SA, Vega A, Rosenstein BS, Teixeira MR; NC-LA PCaP Investigators; Kogevinas M, Cannon-Albright L, Huff C, Multigner L, Kaneva R, Leach RJ, Brenner H, Hsing AW, Kittles RA, Murphy AB, Logothetis CJ, Neuhausen SL, Isaacs WB, Nemesure B, Hennis AJ, Carpten J, Pandha H, De Ruyck K, Xu J, Razack A, Teo SH; Canary PASS Investigators; Newcomb LF, Fowke JH, Neslund-Dudas C, Rybicki BA, Gamulin M, Usmani N, Claessens F, GagoDominguez M, Castelao JE, Townsend PA, Crawford DC, Petrovics G, Casey G, Roobol MJ, Hu JF, Berndt SI, Van Den Eeden SK, Easton DF, Chanock SJ, Co… See abstract for full author list ➔ Darst BF, et al. Among authors: justice ac. medRxiv [Preprint]. 2023 May 15:2023.05.12.23289860. doi: 10.1101/2023.05.12.23289860. medRxiv. 2023. PMID: 37292833 Free PMC article. Updated. Preprint.
Multi-ancestry study of the genetics of problematic alcohol use in >1 million individuals.
Zhou H, Kember RL, Deak JD, Xu H, Toikumo S, Yuan K, Lind PA, Farajzadeh L, Wang L, Hatoum AS, Johnson J, Lee H, Mallard TT, Xu J, Johnston KJA, Johnson EC, Galimberti M, Dao C, Levey DF, Overstreet C, Byrne EM, Gillespie NA, Gordon S, Hickie IB, Whitfield JB, Xu K, Zhao H, Huckins LM, Davis LK, Sanchez-Roige S, Madden PAF, Heath AC, Medland SE, Martin NG, Ge T, Smoller JW, Hougaard DM, Børglum AD, Demontis D, Krystal JH, Gaziano JM, Edenberg HJ, Agrawal A; Million Veteran Program; Justice AC, Stein MB, Kranzler HR, Gelernter J. Zhou H, et al. Among authors: justice ac. medRxiv [Preprint]. 2023 Jan 30:2023.01.24.23284960. doi: 10.1101/2023.01.24.23284960. medRxiv. 2023. PMID: 36747741 Free PMC article. Updated. Preprint.
The genetic architecture of pain intensity in a sample of 598,339 U.S. veterans.
Toikumo S, Vickers-Smith R, Jinwala Z, Xu H, Saini D, Hartwell E, Venegas MP, Sullivan KA, Xu K, Jacobson DA, Gelernter J, Rentsch CT; Million Veteran Program; Stahl E, Cheatle M, Zhou H, Waxman SG, Justice AC, Kember RL, Kranzler HR. Toikumo S, et al. Among authors: justice ac. medRxiv [Preprint]. 2023 Mar 13:2023.03.09.23286958. doi: 10.1101/2023.03.09.23286958. medRxiv. 2023. PMID: 36993749 Free PMC article. Preprint.
Multi-ancestry meta-analysis of tobacco use disorder prioritizes novel candidate risk genes and reveals associations with numerous health outcomes.
Toikumo S, Jennings MV, Pham BK, Lee H, Mallard TT, Bianchi SB, Meredith JJ, Vilar-Ribó L, Xu H, Hatoum AS, Johnson EC, Pazdernik V, Jinwala Z, Pakala SR, Leger BS, Niarchou M, Ehinmowo M; Penn Medicine BioBank, Million Veteran Program, PsycheMERGE Substance Use Disorder Workgroup; Jenkins GD, Batzler A, Pendegraft R, Palmer AA, Zhou H, Biernacka JM, Coombes BJ, Gelernter J, Xu K, Hancock DB, Cox NJ, Smoller JW, Davis LK, Justice AC, Kranzler HR, Kember RL, Sanchez-Roige S. Toikumo S, et al. Among authors: justice ac. medRxiv [Preprint]. 2023 Sep 18:2023.03.27.23287713. doi: 10.1101/2023.03.27.23287713. medRxiv. 2023. PMID: 37034728 Free PMC article. Updated. Preprint.
Diversity and Scale: Genetic Architecture of 2,068 Traits in the VA Million Veteran Program.
Verma A, Huffman JE, Rodriguez A, Conery M, Liu M, Ho YL, Kim Y, Heise DA, Guare L, Panickan VA, Garcon H, Linares F, Costa L, Goethert I, Tipton R, Honerlaw J, Davies L, Whitbourne S, Cohen J, Posner DC, Sangar R, Murray M, Wang X, Dochtermann DR, Devineni P, Shi Y, Nandi TN, Assimes TL, Brunette CA, Carroll RJ, Clifford R, Duvall S, Gelernter J, Hung A, Iyengar SK, Joseph J, Kember R, Kranzler H, Levey D, Luoh SW, Merritt VC, Overstreet C, Deak JD, Grant SFA, Polimanti R, Roussos P, Sun YV, Venkatesh S, Voloudakis G, Justice A, Begoli E, Ramoni R, Tourassi G, Pyarajan S, Tsao PS, O'Donnell CJ, Muralidhar S, Moser J, Casas JP, Bick AG, Zhou W, Cai T, Voight BF, Cho K, Gaziano MJ, Madduri RK, Damrauer SM, Liao KP. Verma A, et al. medRxiv [Preprint]. 2023 Jun 29:2023.06.28.23291975. doi: 10.1101/2023.06.28.23291975. medRxiv. 2023. PMID: 37425708 Free PMC article. Preprint.
Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves cross-ancestry prediction.
Hoffmann TJ, Graff RE, Madduri RK, Rodriguez AA, Cario CL, Feng K, Jiang Y, Wang A, Klein RJ, Pierce BL, Eggener S, Tong L, Blot W, Long J, Rebbeck T, Lachance J, Andrews C, Adebiyi AO, Adusei B, Aisuodionoe-Shadrach OI, Fernandez PW, Jalloh M, Janivara R, Chen WC, Mensah JE, Agalliu I, Berndt SI, Shelley JP, Schaffer K, Machiela MJ, Freedman ND, Huang WY, Li SA, Goodman PJ, Till C, Thompson I, Lilja H, Van Den Eeden SK, Chanock SJ, Mosley JD, Conti DV, Haiman CA, Justice AC, Kachuri L, Witte JS. Hoffmann TJ, et al. Among authors: justice ac. medRxiv [Preprint]. 2023 Oct 30:2023.10.27.23297676. doi: 10.1101/2023.10.27.23297676. medRxiv. 2023. PMID: 37961155 Free PMC article. Preprint.
Absolute and relative excess mortality across demographic and clinical subgroups during the COVID-19 pandemic: an individual-level cohort study from a nationwide healthcare system of US Veterans.
Weinberger DM, Bhaskaran K, Korves C, Lucas BP, Columbo JA, Vashi A, Davies L, Justice AC, Rentsch CT. Weinberger DM, et al. Among authors: justice ac. medRxiv [Preprint]. 2023 May 16:2023.05.12.23289900. doi: 10.1101/2023.05.12.23289900. medRxiv. 2023. PMID: 37293086 Free PMC article. Preprint.
A multi-ancestry genetic study of pain intensity in 598,339 veterans.
Toikumo S, Vickers-Smith R, Jinwala Z, Xu H, Saini D, Hartwell EE, Pavicic M, Sullivan KA, Xu K, Jacobson DA, Gelernter J, Rentsch CT; Million Veteran Program; Stahl E, Cheatle M, Zhou H, Waxman SG, Justice AC, Kember RL, Kranzler HR. Toikumo S, et al. Among authors: justice ac. Nat Med. 2024 Apr;30(4):1075-1084. doi: 10.1038/s41591-024-02839-5. Epub 2024 Mar 1. Nat Med. 2024. PMID: 38429522
Author Correction: A multi-ancestry genetic study of pain intensity in 598,339 veterans.
Toikumo S, Vickers-Smith R, Jinwala Z, Xu H, Saini D, Hartwell EE, Pavicic M, Sullivan KA, Xu K, Jacobson DA, Gelernter J, Rentsch CT; Million Veteran Program; Stahl E, Cheatle M, Zhou H, Waxman SG, Justice AC, Kember RL, Kranzler HR. Toikumo S, et al. Among authors: justice ac. Nat Med. 2024 May 7. doi: 10.1038/s41591-024-03024-4. Online ahead of print. Nat Med. 2024. PMID: 38714900 No abstract available.
528 results