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Excess filaggrin in keratinocytes is removed by extracellular vesicles to prevent premature death and this mechanism can be hijacked by Staphylococcus aureus in a TLR2-dependent fashion.
Kobiela A, Hovhannisyan L, Jurkowska P, de la Serna JB, Bogucka A, Deptuła M, Paul AA, Panek K, Czechowska E, Rychłowski M, Królicka A, Zieliński J, Gabrielsson S, Pikuła M, Trzeciak M, Ogg GS, Gutowska-Owsiak D. Kobiela A, et al. Among authors: jurkowska p. J Extracell Vesicles. 2023 Jun;12(6):e12335. doi: 10.1002/jev2.12335. J Extracell Vesicles. 2023. PMID: 37338870 Free PMC article.