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DNA damage response and cellular senescence in tissues of aging mice.
Wang C, Jurk D, Maddick M, Nelson G, Martin-Ruiz C, von Zglinicki T. Wang C, et al. Among authors: jurk d. Aging Cell. 2009 Jun;8(3):311-23. doi: 10.1111/j.1474-9726.2009.00481.x. Epub 2009 Apr 9. Aging Cell. 2009. PMID: 19627270 Free article.
Adult-onset, short-term dietary restriction reduces cell senescence in mice.
Wang C, Maddick M, Miwa S, Jurk D, Czapiewski R, Saretzki G, Langie SA, Godschalk RW, Cameron K, von Zglinicki T. Wang C, et al. Among authors: jurk d. Aging (Albany NY). 2010 Sep;2(9):555-66. doi: 10.18632/aging.100196. Aging (Albany NY). 2010. PMID: 20844316 Free PMC article.
A senescent cell bystander effect: senescence-induced senescence.
Nelson G, Wordsworth J, Wang C, Jurk D, Lawless C, Martin-Ruiz C, von Zglinicki T. Nelson G, et al. Among authors: jurk d. Aging Cell. 2012 Apr;11(2):345-9. doi: 10.1111/j.1474-9726.2012.00795.x. Epub 2012 Feb 9. Aging Cell. 2012. PMID: 22321662 Free PMC article.
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice.
Jurk D, Wilson C, Passos JF, Oakley F, Correia-Melo C, Greaves L, Saretzki G, Fox C, Lawless C, Anderson R, Hewitt G, Pender SL, Fullard N, Nelson G, Mann J, van de Sluis B, Mann DA, von Zglinicki T. Jurk D, et al. Nat Commun. 2014 Jun 24;2:4172. doi: 10.1038/ncomms5172. Nat Commun. 2014. PMID: 24960204 Free PMC article.
17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization.
Stout MB, Steyn FJ, Jurczak MJ, Camporez JG, Zhu Y, Hawse JR, Jurk D, Palmer AK, Xu M, Pirtskhalava T, Evans GL, de Souza Santos R, Frank AP, White TA, Monroe DG, Singh RJ, Casaclang-Verzosa G, Miller JD, Clegg DJ, LeBrasseur NK, von Zglinicki T, Shulman GI, Tchkonia T, Kirkland JL. Stout MB, et al. Among authors: jurk d. J Gerontol A Biol Sci Med Sci. 2017 Jan;72(1):3-15. doi: 10.1093/gerona/glv309. Epub 2016 Jan 24. J Gerontol A Biol Sci Med Sci. 2017. PMID: 26809497 Free PMC article.
Mitochondria are required for pro-ageing features of the senescent phenotype.
Correia-Melo C, Marques FD, Anderson R, Hewitt G, Hewitt R, Cole J, Carroll BM, Miwa S, Birch J, Merz A, Rushton MD, Charles M, Jurk D, Tait SW, Czapiewski R, Greaves L, Nelson G, Bohlooly-Y M, Rodriguez-Cuenca S, Vidal-Puig A, Mann D, Saretzki G, Quarato G, Green DR, Adams PD, von Zglinicki T, Korolchuk VI, Passos JF. Correia-Melo C, et al. Among authors: jurk d. EMBO J. 2016 Apr 1;35(7):724-42. doi: 10.15252/embj.201592862. Epub 2016 Feb 4. EMBO J. 2016. PMID: 26848154 Free PMC article.
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