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Activation of the Kynurenine Pathway in Human Malignancies Can Be Suppressed by the Cyclin-Dependent Kinase Inhibitor Dinaciclib.
Riess C, Schneider B, Kehnscherper H, Gesche J, Irmscher N, Shokraie F, Classen CF, Wirthgen E, Domanska G, Zimpfer A, Strüder D, Junghanss C, Maletzki C. Riess C, et al. Among authors: junghanss c. Front Immunol. 2020 Feb 14;11:55. doi: 10.3389/fimmu.2020.00055. eCollection 2020. Front Immunol. 2020. PMID: 32117235 Free PMC article.
Combination of the PI3K inhibitor Idelalisib with the conventional cytostatics cytarabine and dexamethasone leads to changes in pathway activation that induce anti-proliferative effects in B lymphoblastic leukaemia cell lines.
Sklarz LM, Gladbach YS, Ernst M, Hamed M, Roolf C, Sender S, Beck J, Schütz E, Fischer S, Struckmann S, Junghanss C, Fuellen G, Murua Escobar H. Sklarz LM, et al. Among authors: junghanss c. Cancer Cell Int. 2020 Aug 12;20:390. doi: 10.1186/s12935-020-01431-4. eCollection 2020. Cancer Cell Int. 2020. PMID: 32817744 Free PMC article.
194 results