Junghanss C - Search Results

1

Healthspan pathway maps in C. elegans and humans highlight transcription, proliferation/biosynthesis and lipids.

Möller S, Saul N, Cohen AA, Köhling R, Sender S, Murua Escobar H, Junghanss C, Cirulli F, Berry A, Antal P, Adler P, Vilo J, Boiani M, Jansen L, Repsilber D, Grabe HJ, Struckmann S, Barrantes I, Hamed M, Wouters B, Schoofs L, Luyten W, Fuellen G. Möller S, et al. Among authors: junghanss c. Aging (Albany NY). 2020 Jul 7;12(13):12534-12581. doi: 10.18632/aging.103514. Epub 2020 Jul 7. Aging (Albany NY). 2020. PMID: 32634117 Free PMC article. Review.

2

The multikinase inhibitor Sorafenib displays significant antiproliferative effects and induces apoptosis via caspase 3, 7 and PARP in B- and T-lymphoblastic cells.

Schult C, Dahlhaus M, Ruck S, Sawitzky M, Amoroso F, Lange S, Etro D, Glass A, Fuellen G, Boldt S, Wolkenhauer O, Neri LM, Freund M, Junghanss C. Schult C, et al. Among authors: junghanss c. BMC Cancer. 2010 Oct 15;10:560. doi: 10.1186/1471-2407-10-560. BMC Cancer. 2010. PMID: 20950443 Free PMC article.

3

Inbred mouse strains reveal biomarkers that are pro-longevity, antilongevity or role switching.

Moeller M, Hirose M, Mueller S, Roolf C, Baltrusch S, Ibrahim S, Junghanss C, Wolkenhauer O, Jaster R, Köhling R, Kunz M, Tiedge M, Schofield PN, Fuellen G. Moeller M, et al. Among authors: junghanss c. Aging Cell. 2014 Aug;13(4):729-38. doi: 10.1111/acel.12226. Epub 2014 May 23. Aging Cell. 2014. PMID: 24862908 Free PMC article.

4

Systems biology approaches in aging research.

Chauhan A, Liebal UW, Vera J, Baltrusch S, Junghanß C, Tiedge M, Fuellen G, Wolkenhauer O, Köhling R. Chauhan A, et al. Among authors: junghanss c. Interdiscip Top Gerontol. 2015;40:155-76. doi: 10.1159/000364981. Epub 2014 Oct 14. Interdiscip Top Gerontol. 2015. PMID: 25341520 Free article. Review.

5

Reduced adolescent-age spatial learning ability associated with elevated juvenile-age superoxide levels in complex I mouse mutants.

Mayer J, Reichart G, Tokay T, Lange F, Baltrusch S, Junghanss C, Wolkenhauer O, Jaster R, Kunz M, Tiedge M, Ibrahim S, Fuellen G, Köhling R. Mayer J, et al. Among authors: junghanss c. PLoS One. 2015 Apr 8;10(4):e0123863. doi: 10.1371/journal.pone.0123863. eCollection 2015. PLoS One. 2015. PMID: 25853418 Free PMC article.

6

Uncoupling protein 2 deficiency results in higher neutrophil counts and lower B-cell counts during aging in mice.

Kretzschmar C, Roolf C, Timmer K, Sekora A, Knübel G, Murua Escobar H, Jaster R, Müller S, Fuellen G, Köhling R, Junghanss C. Kretzschmar C, et al. Among authors: junghanss c. Exp Hematol. 2016 Nov;44(11):1085-1091.e2. doi: 10.1016/j.exphem.2016.08.003. Epub 2016 Aug 17. Exp Hematol. 2016. PMID: 27544660 Free article.

7

Polymorphisms of the murine mitochondrial ND4, CYTB and COX3 genes impact hematopoiesis during aging.

Kretzschmar C, Roolf C, Timmer K, Sekora A, Knübel G, Murua Escobar H, Fuellen G, Ibrahim SM, Tiedge M, Baltrusch S, Jaster R, Köhling R, Junghanss C. Kretzschmar C, et al. Among authors: junghanss c. Oncotarget. 2016 Nov 15;7(46):74460-74472. doi: 10.18632/oncotarget.11952. Oncotarget. 2016. PMID: 27626489 Free PMC article.

8

Polymorphism in Murine mtATP8 Gene Correlates with Decreased Reactive Oxygen Species in Aging Hematopoietic Cells.

Roolf C, Kretzschmar C, Timmer K, Sekora A, Knübel G, Murua Escobar H, Fuellen G, Ibrahim SM, Tiedge M, Baltrusch S, Müller S, Köhling R, Junghanss C. Roolf C, et al. Among authors: junghanss c. In Vivo. 2016 Nov 12;30(6):751-760. doi: 10.21873/invivo.10991. In Vivo. 2016. PMID: 27815458

9

FocusHeuristics - expression-data-driven network optimization and disease gene prediction.

Ernst M, Du Y, Warsow G, Hamed M, Endlich N, Endlich K, Murua Escobar H, Sklarz LM, Sender S, Junghanß C, Möller S, Fuellen G, Struckmann S. Ernst M, et al. Among authors: junghanss c. Sci Rep. 2017 Feb 16;7:42638. doi: 10.1038/srep42638. Sci Rep. 2017. PMID: 28205611 Free PMC article.

10

Phosphoproteome Analysis Reveals Differential Mode of Action of Sorafenib in Wildtype and Mutated FLT3 Acute Myeloid Leukemia (AML) Cells.

Roolf C, Dybowski N, Sekora A, Mueller S, Knuebel G, Tebbe A, Murua Escobar H, Godl K, Junghanss C, Schaab C. Roolf C, et al. Among authors: junghanss c. Mol Cell Proteomics. 2017 Jul;16(7):1365-1376. doi: 10.1074/mcp.M117.067462. Epub 2017 Apr 27. Mol Cell Proteomics. 2017. PMID: 28450419 Free PMC article.

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