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Structure-guided design of a selective inhibitor of the methyltransferase KMT9 with cellular activity.
Wang S, Klein SO, Urban S, Staudt M, Barthes NPF, Willmann D, Bacher J, Sum M, Bauer H, Peng L, Rennar GA, Gratzke C, Schüle KM, Zhang L, Einsle O, Greschik H, MacLeod C, Thomson CG, Jung M, Metzger E, Schüle R. Wang S, et al. Among authors: jung m. Nat Commun. 2024 Jan 2;15(1):43. doi: 10.1038/s41467-023-44243-6. Nat Commun. 2024. PMID: 38167811 Free PMC article.
A novel arginine methyltransferase inhibitor with cellular activity.
Spannhoff A, Machmur R, Heinke R, Trojer P, Bauer I, Brosch G, Schüle R, Hanefeld W, Sippl W, Jung M. Spannhoff A, et al. Among authors: jung m. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4150-3. doi: 10.1016/j.bmcl.2007.05.088. Epub 2007 Jun 3. Bioorg Med Chem Lett. 2007. PMID: 17570663
Current trends in epigenetic drug discovery.
Stolfa DA, Einsle O, Sippl W, Jung M. Stolfa DA, et al. Among authors: jung m. Future Med Chem. 2012 Oct;4(16):2029-37. doi: 10.4155/fmc.12.144. Future Med Chem. 2012. PMID: 23157236
4-Acyl pyrroles: mimicking acetylated lysines in histone code reading.
Lucas X, Wohlwend D, Hügle M, Schmidtkunz K, Gerhardt S, Schüle R, Jung M, Einsle O, Günther S. Lucas X, et al. Among authors: jung m. Angew Chem Int Ed Engl. 2013 Dec 23;52(52):14055-9. doi: 10.1002/anie.201307652. Epub 2013 Nov 24. Angew Chem Int Ed Engl. 2013. PMID: 24272870 No abstract available.
5,364 results