Jung G - Search Results

1

A Recombinant Bispecific CD20×CD95 Antibody With Superior Activity Against Normal and Malignant B-cells.

Nalivaiko K, Hofmann M, Kober K, Teichweyde N, Krammer PH, Rammensee HG, Grosse-Hovest L, Jung G. Nalivaiko K, et al. Among authors: jung g. Mol Ther. 2016 Feb;24(2):298-305. doi: 10.1038/mt.2015.209. Epub 2015 Nov 19. Mol Ther. 2016. PMID: 26581163 Free PMC article.

2

A recombinant bispecific single-chain antibody induces targeted, supra-agonistic CD28-stimulation and tumor cell killing.

Grosse-Hovest L, Hartlapp I, Marwan W, Brem G, Rammensee HG, Jung G. Grosse-Hovest L, et al. Among authors: jung g. Eur J Immunol. 2003 May;33(5):1334-40. doi: 10.1002/eji.200323322. Eur J Immunol. 2003. PMID: 12731059 Free article.

3

Supraagonistic, bispecific single-chain antibody purified from the serum of cloned, transgenic cows induces T-cell-mediated killing of glioblastoma cells in vitro and in vivo.

Grosse-Hovest L, Wick W, Minoia R, Weller M, Rammensee HG, Brem G, Jung G. Grosse-Hovest L, et al. Among authors: jung g. Int J Cancer. 2005 Dec 20;117(6):1060-4. doi: 10.1002/ijc.21294. Int J Cancer. 2005. PMID: 16003729 Free article.

4

Construction of optimized bispecific antibodies for selective activation of the death receptor CD95.

Herrmann T, Grosse-Hovest L, Otz T, Krammer PH, Rammensee HG, Jung G. Herrmann T, et al. Among authors: jung g. Cancer Res. 2008 Feb 15;68(4):1221-7. doi: 10.1158/0008-5472.CAN-07-6175. Cancer Res. 2008. PMID: 18281499

5

Characterization of a bispecific FLT3 X CD3 antibody in an improved, recombinant format for the treatment of leukemia.

Durben M, Schmiedel D, Hofmann M, Vogt F, Nübling T, Pyz E, Bühring HJ, Rammensee HG, Salih HR, Große-Hovest L, Jung G. Durben M, et al. Among authors: jung g. Mol Ther. 2015 Apr;23(4):648-55. doi: 10.1038/mt.2015.2. Epub 2015 Jan 12. Mol Ther. 2015. PMID: 25578618 Free PMC article.

6

Reduction of Minimal Residual Disease in Pediatric B-lineage Acute Lymphoblastic Leukemia by an Fc-optimized CD19 Antibody.

Seidel UJ, Schlegel P, Grosse-Hovest L, Hofmann M, Aulwurm S, Pyz E, Schuster FR, Meisel R, Ebinger M, Feuchtinger T, Teltschik HM, Witte KE, Schwarze CP, Rammensee HG, Handgretinger R, Jung G, Lang P. Seidel UJ, et al. Among authors: jung g. Mol Ther. 2016 Sep;24(9):1634-43. doi: 10.1038/mt.2016.141. Epub 2016 Jul 6. Mol Ther. 2016. PMID: 27380762 Free PMC article.

7

Target cell-restricted triggering of the CD95 (APO-1/Fas) death receptor with bispecific antibody fragments.

Jung G, Grosse-Hovest L, Krammer PH, Rammensee HG. Jung G, et al. Cancer Res. 2001 Mar 1;61(5):1846-8. Cancer Res. 2001. PMID: 11280736

8

A bispecific single-chain antibody that mediates target cell-restricted, supra-agonistic CD28 stimulation and killing of lymphoma cells.

Otz T, Grosse-Hovest L, Hofmann M, Rammensee HG, Jung G. Otz T, et al. Among authors: jung g. Leukemia. 2009 Jan;23(1):71-7. doi: 10.1038/leu.2008.271. Epub 2008 Oct 2. Leukemia. 2009. PMID: 18830257

9

Tocilizumab, but not dexamethasone, prevents CRS without affecting antitumor activity of bispecific antibodies.

Kauer J, Hörner S, Osburg L, Müller S, Märklin M, Heitmann JS, Zekri L, Rammensee HG, Salih HR, Jung G. Kauer J, et al. Among authors: jung g. J Immunother Cancer. 2020 May;8(1):e000621. doi: 10.1136/jitc-2020-000621. J Immunother Cancer. 2020. PMID: 32474413 Free PMC article.

10

An IgG-based bispecific antibody for improved dual targeting in PSMA-positive cancer.

Zekri L, Vogt F, Osburg L, Müller S, Kauer J, Manz T, Pflügler M, Maurer A, Heitmann JS, Hagelstein I, Märklin M, Hörner S, Todenhöfer T, Calaminus C, Stenzl A, Pichler B, la Fougère C, Schneider MA, Rammensee HG, Zender L, Sipos B, Salih HR, Jung G. Zekri L, et al. Among authors: jung g. EMBO Mol Med. 2021 Feb 5;13(2):e11902. doi: 10.15252/emmm.201911902. Epub 2020 Dec 29. EMBO Mol Med. 2021. PMID: 33372710 Free PMC article.

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