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Anti-metastatic immunotherapy based on mucosal administration of flagellin and immunomodulatory P10.
de Melo FM, Braga CJ, Pereira FV, Maricato JT, Origassa CS, Souza MF, Melo AC, Silva P, Tomaz SL, Gimenes KP, Scutti JA, Juliano MA, Zamboni DS, Câmara NO, Travassos LR, Ferreira LC, Rodrigues EG. de Melo FM, et al. Among authors: juliano ma. Immunol Cell Biol. 2015 Jan;93(1):86-98. doi: 10.1038/icb.2014.74. Epub 2014 Sep 16. Immunol Cell Biol. 2015. PMID: 25223833
A natural bacterial-derived product, the metalloprotease arazyme, inhibits metastatic murine melanoma by inducing MMP-8 cross-reactive antibodies.
Pereira FV, Ferreira-Guimarães CA, Paschoalin T, Scutti JA, Melo FM, Silva LS, Melo AC, Silva P, Tiago M, Matsuo AL, Juliano L, Juliano MA, Carmona AK, Travassos LR, Rodrigues EG. Pereira FV, et al. Among authors: juliano l, juliano ma. PLoS One. 2014 Apr 30;9(4):e96141. doi: 10.1371/journal.pone.0096141. eCollection 2014. PLoS One. 2014. PMID: 24788523 Free PMC article.
β-Actin-binding complementarity-determining region 2 of variable heavy chain from monoclonal antibody C7 induces apoptosis in several human tumor cells and is protective against metastatic melanoma.
Arruda DC, Santos LC, Melo FM, Pereira FV, Figueiredo CR, Matsuo AL, Mortara RA, Juliano MA, Rodrigues EG, Dobroff AS, Polonelli L, Travassos LR. Arruda DC, et al. Among authors: juliano ma. J Biol Chem. 2012 Apr 27;287(18):14912-22. doi: 10.1074/jbc.M111.322362. Epub 2012 Feb 13. J Biol Chem. 2012. PMID: 22334655 Free PMC article.
TLR4-mediated immunomodulatory properties of the bacterial metalloprotease arazyme in preclinical tumor models.
Pereira FV, Melo AC, de Melo FM, Mourão-Sá D, Silva P, Berzaghi R, Herbozo CC, Coelho-Dos-Reis J, Scutti JA, Origassa CS, Pereira RM, Juliano L, Juliano MA, Carmona AK, Câmara NO, Tsuji M, Travassos LR, Rodrigues EG. Pereira FV, et al. Among authors: juliano l, juliano ma. Oncoimmunology. 2016 May 5;5(7):e1178420. doi: 10.1080/2162402X.2016.1178420. eCollection 2016 Jul. Oncoimmunology. 2016. PMID: 27622031 Free PMC article.
Differential Antitumor Effects of IgG and IgM Monoclonal Antibodies and Their Synthetic Complementarity-Determining Regions Directed to New Targets of B16F10-Nex2 Melanoma Cells.
Dobroff AS, Rodrigues EG, Juliano MA, Friaça DM, Nakayasu ES, Almeida IC, Mortara RA, Jacysyn JF, Amarante-Mendes GP, Magliani W, Conti S, Polonelli L, Travassos LR. Dobroff AS, et al. Among authors: juliano ma. Transl Oncol. 2010 Aug 1;3(4):204-17. doi: 10.1593/tlo.09316. Transl Oncol. 2010. PMID: 20689762 Free PMC article.
352 results