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21-Hydroxypregnane 21-O-malonylation, a crucial step in cardenolide biosynthesis, can be achieved by substrate-promiscuous BAHD-type phenolic glucoside malonyltransferases from Arabidopsis thaliana and homolog proteins from Digitalis lanata.
Tropper M, Höhn S, Wolf LS, Fritsch J, Kastner-Detter N, Rieck C, Munkert J, Meitinger N, Lanig H, Kreis W. Tropper M, et al. Among authors: fritsch j. Phytochemistry. 2021 Jul;187:112710. doi: 10.1016/j.phytochem.2021.112710. Epub 2021 Apr 28. Phytochemistry. 2021. PMID: 33930670
Epithelial TLR4 Signaling Activates DUOX2 to Induce Microbiota-Driven Tumorigenesis.
Burgueño JF, Fritsch J, González EE, Landau KS, Santander AM, Fernández I, Hazime H, Davies JM, Santaolalla R, Phillips MC, Diaz S, Dheer R, Brito N, Pignac-Kobinger J, Fernández E, Conner GE, Abreu MT. Burgueño JF, et al. Among authors: fritsch j. Gastroenterology. 2021 Feb;160(3):797-808.e6. doi: 10.1053/j.gastro.2020.10.031. Epub 2020 Oct 24. Gastroenterology. 2021. PMID: 33127391 Free PMC article.
Low-Fat, High-Fiber Diet Reduces Markers of Inflammation and Dysbiosis and Improves Quality of Life in Patients With Ulcerative Colitis.
Fritsch J, Garces L, Quintero MA, Pignac-Kobinger J, Santander AM, Fernández I, Ban YJ, Kwon D, Phillips MC, Knight K, Mao Q, Santaolalla R, Chen XS, Maruthamuthu M, Solis N, Damas OM, Kerman DH, Deshpande AR, Lewis JE, Chen C, Abreu MT. Fritsch J, et al. Clin Gastroenterol Hepatol. 2021 Jun;19(6):1189-1199.e30. doi: 10.1016/j.cgh.2020.05.026. Epub 2020 May 20. Clin Gastroenterol Hepatol. 2021. PMID: 32445952 Free article. Clinical Trial.
Candida in IBD: Friend or Foe?
Fritsch J, Abreu MT. Fritsch J, et al. Cell Host Microbe. 2020 May 13;27(5):689-691. doi: 10.1016/j.chom.2020.04.018. Cell Host Microbe. 2020. PMID: 32407705 Free article.
Expression of SARS-CoV-2 Entry Molecules ACE2 and TMPRSS2 in the Gut of Patients With IBD.
Burgueño JF, Reich A, Hazime H, Quintero MA, Fernandez I, Fritsch J, Santander AM, Brito N, Damas OM, Deshpande A, Kerman DH, Zhang L, Gao Z, Ban Y, Wang L, Pignac-Kobinger J, Abreu MT. Burgueño JF, et al. Among authors: fritsch j. Inflamm Bowel Dis. 2020 May 12;26(6):797-808. doi: 10.1093/ibd/izaa085. Inflamm Bowel Dis. 2020. PMID: 32333601 Free PMC article.
13 results