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A single-domain intrabody targeting the follicle-stimulating hormone receptor impacts FSH-induced G protein-dependent signalling.
FEBS Lett. 2024 Jan;598(2):220-232. doi: 10.1002/1873-3468.14765. Epub 2023 Nov 3.
FEBS Lett. 2024.
PMID: 37923554
Intracellular VHHs to monitor and modulate GPCR signaling.
Raynaud P, Gauthier C, Jugnarain V, Jean-Alphonse F, Reiter E, Bruneau G, Crépieux P.
Raynaud P, et al. Among authors: jugnarain v.
Front Endocrinol (Lausanne). 2022 Nov 16;13:1048601. doi: 10.3389/fendo.2022.1048601. eCollection 2022.
Front Endocrinol (Lausanne). 2022.
PMID: 36465650
Free PMC article.
Review.
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Combined Multiplexed Phage Display, High-Throughput Sequencing, and Functional Assays as a Platform for Identifying Modulatory VHHs Targeting the FSHR.
Zehnaker A, Vallet A, Gourdon J, Sarti C, Jugnarain V, Haj Hassan M, Mathias L, Gauthier C, Raynaud P, Boulo T, Beauclair L, Bigot Y, Casarini L, Crépieux P, Poupon A, Piégu B, Jean-Alphonse F, Bruneau G, Reiter É.
Zehnaker A, et al. Among authors: jugnarain v.
Int J Mol Sci. 2023 Nov 4;24(21):15961. doi: 10.3390/ijms242115961.
Int J Mol Sci. 2023.
PMID: 37958944
Free PMC article.
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An intracellular VHH targeting the Luteinizing Hormone receptor modulates G protein-dependent signaling and steroidogenesis.
Gauthier C, Raynaud P, Jean-Alphonse F, Vallet A, Vaugrente O, Jugnarain V, Boulo T, Gauthier C, Reiter E, Bruneau G, Crépieux P.
Gauthier C, et al. Among authors: jugnarain v.
Mol Cell Endocrinol. 2024 Apr 15;589:112235. doi: 10.1016/j.mce.2024.112235. Online ahead of print.
Mol Cell Endocrinol. 2024.
PMID: 38621656
Free article.
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Purine containing carbonucleoside phosphonate analogues as novel chemotype for Plasmodium falciparum Inhibition.
Mohamed BS, Nguyen MC, Wein S, Uttaro JP, Robert X, Violot S, Ballut L, Jugnarain V, Mathé C, Cerdan R, Aghajari N, Peyrottes S.
Mohamed BS, et al. Among authors: jugnarain v.
Eur J Med Chem. 2023 Oct 5;258:115581. doi: 10.1016/j.ejmech.2023.115581. Epub 2023 Jun 25.
Eur J Med Chem. 2023.
PMID: 37402342
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Exploring molecular determinants of polysaccharide lyase family 6-1 enzyme activity.
Violot S, Galisson F, Carrique L, Jugnarain V, Conchou L, Robert X, Thureau A, Helbert W, Aghajari N, Ballut L.
Violot S, et al. Among authors: jugnarain v.
Glycobiology. 2021 Dec 18;31(11):1557-1570. doi: 10.1093/glycob/cwab073.
Glycobiology. 2021.
PMID: 34245266
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Disulfide reduction in CD4 domain 1 or 2 is essential for interaction with HIV glycoprotein 120 (gp120), which impairs thioredoxin-driven CD4 dimerization.
Cerutti N, Killick M, Jugnarain V, Papathanasopoulos M, Capovilla A.
Cerutti N, et al. Among authors: jugnarain v.
J Biol Chem. 2014 Apr 11;289(15):10455-10465. doi: 10.1074/jbc.M113.539353. Epub 2014 Feb 18.
J Biol Chem. 2014.
PMID: 24550395
Free PMC article.
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