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Intracellular VHHs to monitor and modulate GPCR signaling.
Raynaud P, Gauthier C, Jugnarain V, Jean-Alphonse F, Reiter E, Bruneau G, Crépieux P. Raynaud P, et al. Among authors: jugnarain v. Front Endocrinol (Lausanne). 2022 Nov 16;13:1048601. doi: 10.3389/fendo.2022.1048601. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36465650 Free PMC article. Review.
Combined Multiplexed Phage Display, High-Throughput Sequencing, and Functional Assays as a Platform for Identifying Modulatory VHHs Targeting the FSHR.
Zehnaker A, Vallet A, Gourdon J, Sarti C, Jugnarain V, Haj Hassan M, Mathias L, Gauthier C, Raynaud P, Boulo T, Beauclair L, Bigot Y, Casarini L, Crépieux P, Poupon A, Piégu B, Jean-Alphonse F, Bruneau G, Reiter É. Zehnaker A, et al. Among authors: jugnarain v. Int J Mol Sci. 2023 Nov 4;24(21):15961. doi: 10.3390/ijms242115961. Int J Mol Sci. 2023. PMID: 37958944 Free PMC article.
An intracellular VHH targeting the Luteinizing Hormone receptor modulates G protein-dependent signaling and steroidogenesis.
Gauthier C, Raynaud P, Jean-Alphonse F, Vallet A, Vaugrente O, Jugnarain V, Boulo T, Gauthier C, Reiter E, Bruneau G, Crépieux P. Gauthier C, et al. Among authors: jugnarain v. Mol Cell Endocrinol. 2024 Apr 15;589:112235. doi: 10.1016/j.mce.2024.112235. Online ahead of print. Mol Cell Endocrinol. 2024. PMID: 38621656 Free article.