Jude KM - Search Results

1

Design of cell-type-specific hyperstable IL-4 mimetics via modular de novo scaffolds.

Yang H, Ulge UY, Quijano-Rubio A, Bernstein ZJ, Maestas DR, Chun JH, Wang W, Lin JX, Jude KM, Singh S, Orcutt-Jahns BT, Li P, Mou J, Chung L, Kuo YH, Ali YH, Meyer AS, Grayson WL, Heller NM, Garcia KC, Leonard WJ, Silva DA, Elisseeff JH, Baker D, Spangler JB. Yang H, et al. Among authors: jude km. Nat Chem Biol. 2023 Sep;19(9):1127-1137. doi: 10.1038/s41589-023-01313-6. Epub 2023 Apr 6. Nat Chem Biol. 2023. PMID: 37024727 Free PMC article.

2

Ultrahigh resolution crystal structures of human carbonic anhydrases I and II complexed with "two-prong" inhibitors reveal the molecular basis of high affinity.

Jude KM, Banerjee AL, Haldar MK, Manokaran S, Roy B, Mallik S, Srivastava DK, Christianson DW. Jude KM, et al. J Am Chem Soc. 2006 Mar 8;128(9):3011-8. doi: 10.1021/ja057257n. J Am Chem Soc. 2006. PMID: 16506782 Free PMC article.

3

Probing the role of the hyper-reactive histidine residue of arginase.

Colleluori DM, Reczkowski RS, Emig FA, Cama E, Cox JD, Scolnick LR, Compher K, Jude K, Han S, Viola RE, Christianson DW, Ash DE. Colleluori DM, et al. Arch Biochem Biophys. 2005 Dec 1;444(1):15-26. doi: 10.1016/j.abb.2005.09.009. Epub 2005 Oct 13. Arch Biochem Biophys. 2005. PMID: 16266687

4

Structural biology. Structural basis for Notch1 engagement of Delta-like 4.

Luca VC, Jude KM, Pierce NW, Nachury MV, Fischer S, Garcia KC. Luca VC, et al. Among authors: jude km. Science. 2015 Feb 20;347(6224):847-53. doi: 10.1126/science.1261093. Science. 2015. PMID: 25700513 Free PMC article.

5

Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor.

Burg JS, Ingram JR, Venkatakrishnan AJ, Jude KM, Dukkipati A, Feinberg EN, Angelini A, Waghray D, Dror RO, Ploegh HL, Garcia KC. Burg JS, et al. Among authors: jude km. Science. 2015 Mar 6;347(6226):1113-7. doi: 10.1126/science.aaa5026. Science. 2015. PMID: 25745166 Free PMC article.

6

Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms.

Spangler JB, Tomala J, Luca VC, Jude KM, Dong S, Ring AM, Votavova P, Pepper M, Kovar M, Garcia KC. Spangler JB, et al. Among authors: jude km. Immunity. 2015 May 19;42(5):815-25. doi: 10.1016/j.immuni.2015.04.015. Immunity. 2015. PMID: 25992858 Free PMC article.

7

Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency.

Moraga I, Richter D, Wilmes S, Winkelmann H, Jude K, Thomas C, Suhoski MM, Engleman EG, Piehler J, Garcia KC. Moraga I, et al. Sci Signal. 2015 Nov 10;8(402):ra114. doi: 10.1126/scisignal.aab2677. Sci Signal. 2015. PMID: 26554818 Free PMC article.

8

The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity.

Mendoza JL, Schneider WM, Hoffmann HH, Vercauteren K, Jude KM, Xiong A, Moraga I, Horton TM, Glenn JS, de Jong YP, Rice CM, Garcia KC. Mendoza JL, et al. Among authors: jude km. Immunity. 2017 Mar 21;46(3):379-392. doi: 10.1016/j.immuni.2017.02.017. Immunity. 2017. PMID: 28329704 Free PMC article.

9

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes.

Sockolosky JT, Trotta E, Parisi G, Picton L, Su LL, Le AC, Chhabra A, Silveria SL, George BM, King IC, Tiffany MR, Jude K, Sibener LV, Baker D, Shizuru JA, Ribas A, Bluestone JA, Garcia KC. Sockolosky JT, et al. Science. 2018 Mar 2;359(6379):1037-1042. doi: 10.1126/science.aar3246. Science. 2018. PMID: 29496879 Free PMC article.

10

Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy.

Miles TF, Spiess K, Jude KM, Tsutsumi N, Burg JS, Ingram JR, Waghray D, Hjorto GM, Larsen O, Ploegh HL, Rosenkilde MM, Garcia KC. Miles TF, et al. Among authors: jude km. Elife. 2018 Jun 8;7:e35850. doi: 10.7554/eLife.35850. Elife. 2018. PMID: 29882741 Free PMC article.

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