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Quantitative measurement of the requirement of diverse protein degradation pathways in MHC class I peptide presentation.
Mamrosh JL, Sherman DJ, Cohen JR, Johnston JA, Joubert MK, Li J, Lipford JR, Lomenick B, Moradian A, Prabhu S, Sweredoski MJ, Vander Lugt B, Verma R, Deshaies RJ. Mamrosh JL, et al. Among authors: joubert mk. Sci Adv. 2023 Jun 23;9(25):eade7890. doi: 10.1126/sciadv.ade7890. Epub 2023 Jun 23. Sci Adv. 2023. PMID: 37352349 Free PMC article.
A High Threshold of Biotherapeutic Aggregate Numbers is Needed to Induce an Immunogenic Response In Vitro, In Vivo, and in the Clinic.
Cohen JR, Brych SR, Prabhu S, Bi V, Elbaradei A, Tokuda JM, Xiang C, Hokom M, Cui X, Ly C, Amos N, Sun J, Calamba D, Herskovitz J, Capili A, Nourbakhsh K, Merlo A, Carreon J, Wypych J, Narhi LO, Jawa V, Joubert MK. Cohen JR, et al. Among authors: joubert mk. Pharm Res. 2024 Apr;41(4):651-672. doi: 10.1007/s11095-024-03678-2. Epub 2024 Mar 22. Pharm Res. 2024. PMID: 38519817
Immunogenicity of Therapeutic Protein Aggregates.
Moussa EM, Panchal JP, Moorthy BS, Blum JS, Joubert MK, Narhi LO, Topp EM. Moussa EM, et al. Among authors: joubert mk. J Pharm Sci. 2016 Feb;105(2):417-430. doi: 10.1016/j.xphs.2015.11.002. J Pharm Sci. 2016. PMID: 26869409 Review.
Mouse Models for Assessing Protein Immunogenicity: Lessons and Challenges.
Jiskoot W, Kijanka G, Randolph TW, Carpenter JF, Koulov AV, Mahler HC, Joubert MK, Jawa V, Narhi LO. Jiskoot W, et al. Among authors: joubert mk. J Pharm Sci. 2016 May;105(5):1567-1575. doi: 10.1016/j.xphs.2016.02.031. Epub 2016 Apr 1. J Pharm Sci. 2016. PMID: 27044944 Free PMC article. Review.
27 results