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Development of a scalable and robust AEX method for enriched rAAV preparations in genome-containing VCs of serotypes 5, 6, 8, and 9.
Mol Ther Methods Clin Dev. 2021 Mar 23;21:341-356. doi: 10.1016/j.omtm.2021.03.016. eCollection 2021 Jun 11.
Mol Ther Methods Clin Dev. 2021.
PMID: 33898632
Free PMC article.
Achieving High-Yield Production of Functional AAV5 Gene Delivery Vectors via Fedbatch in an Insect Cell-One Baculovirus System.
Joshi PRH, Cervera L, Ahmed I, Kondratov O, Zolotukhin S, Schrag J, Chahal PS, Kamen AA.
Joshi PRH, et al.
Mol Ther Methods Clin Dev. 2019 Feb 16;13:279-289. doi: 10.1016/j.omtm.2019.02.003. eCollection 2019 Jun 14.
Mol Ther Methods Clin Dev. 2019.
PMID: 30886878
Free PMC article.
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Development and Validation of an Anion Exchange High-Performance Liquid Chromatography Method for Analysis of Empty Capsids and Capsids Encapsidating Genetic Material in a Purified Preparation of Recombinant Adeno-Associated Virus Serotype 5.
Joshi PRH, Bernier A, Chahal PS, Kamen A.
Joshi PRH, et al.
Hum Gene Ther. 2021 Nov;32(21-22):1390-1402. doi: 10.1089/hum.2020.317. Epub 2021 Jun 11.
Hum Gene Ther. 2021.
PMID: 33860673
Free PMC article.
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Advancements in molecular design and bioprocessing of recombinant adeno-associated virus gene delivery vectors using the insect-cell baculovirus expression platform.
Joshi PRH, Venereo-Sanchez A, Chahal PS, Kamen AA.
Joshi PRH, et al.
Biotechnol J. 2021 Apr;16(4):e2000021. doi: 10.1002/biot.202000021. Epub 2021 Jan 25.
Biotechnol J. 2021.
PMID: 33277815
Review.
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