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Elucidating the cellular uptake mechanisms of heptamethine cyanine dye analogues for their use as an anticancer drug-carrier molecule for the treatment of glioblastoma.
Cooper E, Choi PJ, Hwang K, Nam KM, Kim CY, Shaban T, Schweder P, Mee E, Correia J, Turner C, Faull RLM, Denny WA, Noguchi K, Dragunow M, Jose J, Park TI. Cooper E, et al. Among authors: jose j. Chem Biol Drug Des. 2023 Mar;101(3):696-716. doi: 10.1111/cbdd.14171. Epub 2022 Nov 29. Chem Biol Drug Des. 2023. PMID: 36323652
Heptamethine Cyanine Dye Mediated Drug Delivery: Hype or Hope.
Choi PJ, Park TIH, Cooper E, Dragunow M, Denny WA, Jose J. Choi PJ, et al. Among authors: jose j. Bioconjug Chem. 2020 Jul 15;31(7):1724-1739. doi: 10.1021/acs.bioconjchem.0c00302. Epub 2020 Jun 24. Bioconjug Chem. 2020. PMID: 32530288 Review.
Single-cell image analysis reveals over-expression of organic anion transporting polypeptides (OATPs) in human glioblastoma tissue.
Cooper E, Woolf Z, Swanson MEV, Correia J, Schweder P, Mee E, Heppner P, Turner C, Faull RLM, Scotter EL, Denny WA, Choi PJ, Dragunow M, Jose J, Park TI. Cooper E, et al. Among authors: jose j. Neurooncol Adv. 2022 Oct 14;4(1):vdac166. doi: 10.1093/noajnl/vdac166. eCollection 2022 Jan-Dec. Neurooncol Adv. 2022. PMID: 36382105 Free PMC article.
Involvement of the tumour necrosis factor receptor system in glioblastoma cell death induced by palbociclib-heptamethine cyanine dye conjugate.
Cooper E, Oyagawa CRM, Johnson R, Choi PJ, Foliaki JM, Correia J, Schweder P, Heppner P, Mee E, Turner C, Faull R, Denny WA, Dragunow M, Jose J, Park TI. Cooper E, et al. Among authors: jose j. Cell Commun Signal. 2024 Jan 11;22(1):30. doi: 10.1186/s12964-023-01277-z. Cell Commun Signal. 2024. PMID: 38212807 Free PMC article.
Fragment-based and structure-guided discovery of perforin inhibitors.
Jose J, Law RHP, Leung EWW, Wai DCC, Akhlaghi H, Chandrashekaran IR, Caradoc-Davies TT, Voskoboinik I, Feutrill J, Middlemiss D, Jeevarajah D, Bashtannyk-Puhalovich T, Giddens AC, Lee TW, Jamieson SMF, Trapani JA, Whisstock JC, Spicer JA, Norton RS. Jose J, et al. Eur J Med Chem. 2023 Dec 5;261:115786. doi: 10.1016/j.ejmech.2023.115786. Epub 2023 Sep 1. Eur J Med Chem. 2023. PMID: 37716187 Free article.
Benzenesulphonamide inhibitors of the cytolytic protein perforin.
Spicer JA, Miller CK, O'Connor PD, Jose J, Huttunen KM, Jaiswal JK, Denny WA, Akhlaghi H, Browne KA, Trapani JA. Spicer JA, et al. Among authors: jose j. Bioorg Med Chem Lett. 2017 Feb 15;27(4):1050-1054. doi: 10.1016/j.bmcl.2016.12.057. Epub 2016 Dec 23. Bioorg Med Chem Lett. 2017. PMID: 28110869 Free PMC article.
Substituted arylsulphonamides as inhibitors of perforin-mediated lysis.
Spicer JA, Miller CK, O'Connor PD, Jose J, Huttunen KM, Jaiswal JK, Denny WA, Akhlaghi H, Browne KA, Trapani JA. Spicer JA, et al. Among authors: jose j. Eur J Med Chem. 2017 Sep 8;137:139-155. doi: 10.1016/j.ejmech.2017.05.048. Epub 2017 May 26. Eur J Med Chem. 2017. PMID: 28582670 Free PMC article.
1,221 results