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RX-3117 (Fluorocyclopentenyl-Cytosine)-Mediated Down-Regulation of DNA Methyltransferase 1 Leads to Protein Expression of Tumor-Suppressor Genes and Increased Functionality of the Proton-Coupled Folate Carrier.
Int J Mol Sci. 2020 Apr 14;21(8):2717. doi: 10.3390/ijms21082717.
Int J Mol Sci. 2020.
PMID: 32295203
Free PMC article.
The Cytidine Analog Fluorocyclopentenylcytosine (RX-3117) Is Activated by Uridine-Cytidine Kinase 2.
Sarkisjan D, Julsing JR, Smid K, de Klerk D, van Kuilenburg AB, Meinsma R, Lee YB, Kim DJ, Peters GJ.
Sarkisjan D, et al. Among authors: julsing jr.
PLoS One. 2016 Sep 9;11(9):e0162901. doi: 10.1371/journal.pone.0162901. eCollection 2016.
PLoS One. 2016.
PMID: 27612203
Free PMC article.
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