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Direct detection of early-stage cancers using circulating tumor DNA.
Phallen J, Sausen M, Adleff V, Leal A, Hruban C, White J, Anagnostou V, Fiksel J, Cristiano S, Papp E, Speir S, Reinert T, Orntoft MW, Woodward BD, Murphy D, Parpart-Li S, Riley D, Nesselbush M, Sengamalay N, Georgiadis A, Li QK, Madsen MR, Mortensen FV, Huiskens J, Punt C, van Grieken N, Fijneman R, Meijer G, Husain H, Scharpf RB, Diaz LA Jr, Jones S, Angiuoli S, Ørntoft T, Nielsen HJ, Andersen CL, Velculescu VE. Phallen J, et al. Among authors: jones s. Sci Transl Med. 2017 Aug 16;9(403):eaan2415. doi: 10.1126/scitranslmed.aan2415. Sci Transl Med. 2017. PMID: 28814544 Free PMC article.
Personalized genomic analyses for cancer mutation discovery and interpretation.
Jones S, Anagnostou V, Lytle K, Parpart-Li S, Nesselbush M, Riley DR, Shukla M, Chesnick B, Kadan M, Papp E, Galens KG, Murphy D, Zhang T, Kann L, Sausen M, Angiuoli SV, Diaz LA Jr, Velculescu VE. Jones S, et al. Sci Transl Med. 2015 Apr 15;7(283):283ra53. doi: 10.1126/scitranslmed.aaa7161. Sci Transl Med. 2015. PMID: 25877891 Free PMC article.
A machine learning approach for somatic mutation discovery.
Wood DE, White JR, Georgiadis A, Van Emburgh B, Parpart-Li S, Mitchell J, Anagnostou V, Niknafs N, Karchin R, Papp E, McCord C, LoVerso P, Riley D, Diaz LA Jr, Jones S, Sausen M, Velculescu VE, Angiuoli SV. Wood DE, et al. Among authors: jones s. Sci Transl Med. 2018 Sep 5;10(457):eaar7939. doi: 10.1126/scitranslmed.aar7939. Sci Transl Med. 2018. PMID: 30185652 Free PMC article.
Noninvasive Detection of Microsatellite Instability and High Tumor Mutation Burden in Cancer Patients Treated with PD-1 Blockade.
Georgiadis A, Durham JN, Keefer LA, Bartlett BR, Zielonka M, Murphy D, White JR, Lu S, Verner EL, Ruan F, Riley D, Anders RA, Gedvilaite E, Angiuoli S, Jones S, Velculescu VE, Le DT, Diaz LA Jr, Sausen M. Georgiadis A, et al. Among authors: jones s. Clin Cancer Res. 2019 Dec 1;25(23):7024-7034. doi: 10.1158/1078-0432.CCR-19-1372. Epub 2019 Sep 10. Clin Cancer Res. 2019. PMID: 31506389 Free PMC article.
Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients.
Sausen M, Phallen J, Adleff V, Jones S, Leary RJ, Barrett MT, Anagnostou V, Parpart-Li S, Murphy D, Kay Li Q, Hruban CA, Scharpf R, White JR, O'Dwyer PJ, Allen PJ, Eshleman JR, Thompson CB, Klimstra DS, Linehan DC, Maitra A, Hruban RH, Diaz LA Jr, Von Hoff DD, Johansen JS, Drebin JA, Velculescu VE. Sausen M, et al. Among authors: jones s. Nat Commun. 2015 Jul 7;6:7686. doi: 10.1038/ncomms8686. Nat Commun. 2015. PMID: 26154128 Free PMC article.
The genomic landscape of response to EGFR blockade in colorectal cancer.
Bertotti A, Papp E, Jones S, Adleff V, Anagnostou V, Lupo B, Sausen M, Phallen J, Hruban CA, Tokheim C, Niknafs N, Nesselbush M, Lytle K, Sassi F, Cottino F, Migliardi G, Zanella ER, Ribero D, Russolillo N, Mellano A, Muratore A, Paraluppi G, Salizzoni M, Marsoni S, Kragh M, Lantto J, Cassingena A, Li QK, Karchin R, Scharpf R, Sartore-Bianchi A, Siena S, Diaz LA Jr, Trusolino L, Velculescu VE. Bertotti A, et al. Among authors: jones s. Nature. 2015 Oct 8;526(7572):263-7. doi: 10.1038/nature14969. Epub 2015 Sep 30. Nature. 2015. PMID: 26416732 Free PMC article.
High grade serous ovarian carcinomas originate in the fallopian tube.
Labidi-Galy SI, Papp E, Hallberg D, Niknafs N, Adleff V, Noe M, Bhattacharya R, Novak M, Jones S, Phallen J, Hruban CA, Hirsch MS, Lin DI, Schwartz L, Maire CL, Tille JC, Bowden M, Ayhan A, Wood LD, Scharpf RB, Kurman R, Wang TL, Shih IM, Karchin R, Drapkin R, Velculescu VE. Labidi-Galy SI, et al. Among authors: jones s. Nat Commun. 2017 Oct 23;8(1):1093. doi: 10.1038/s41467-017-00962-1. Nat Commun. 2017. PMID: 29061967 Free PMC article.
Automated next-generation profiling of genomic alterations in human cancers.
Keefer LA, White JR, Wood DE, Gerding KMR, Valkenburg KC, Riley D, Gault C, Papp E, Vollmer CM, Greer A, Hernandez J, McGregor PM 3rd, Zingone A, Ryan BM, Deak K, McCall SJ, Datto MB, Prescott JL, Thompson JF, Cerqueira GC, Jones S, Simmons JK, McElhinny A, Dickey J, Angiuoli SV, Diaz LA Jr, Velculescu VE, Sausen M. Keefer LA, et al. Among authors: jones s. Nat Commun. 2022 May 20;13(1):2830. doi: 10.1038/s41467-022-30380-x. Nat Commun. 2022. PMID: 35595835 Free PMC article.
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