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Page 1
Posttranscriptional control of T cell effector function by aerobic glycolysis.
Chang CH, Curtis JD, Maggi LB Jr, Faubert B, Villarino AV, O'Sullivan D, Huang SC, van der Windt GJ, Blagih J, Qiu J, Weber JD, Pearce EJ, Jones RG, Pearce EL. Chang CH, et al. Among authors: jones rg. Cell. 2013 Jun 6;153(6):1239-51. doi: 10.1016/j.cell.2013.05.016. Cell. 2013. PMID: 23746840 Free PMC article.
CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability.
van der Windt GJ, O'Sullivan D, Everts B, Huang SC, Buck MD, Curtis JD, Chang CH, Smith AM, Ai T, Faubert B, Jones RG, Pearce EJ, Pearce EL. van der Windt GJ, et al. Among authors: jones rg. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14336-41. doi: 10.1073/pnas.1221740110. Epub 2013 Aug 12. Proc Natl Acad Sci U S A. 2013. PMID: 23940348 Free PMC article.
The miR-17∼92 microRNA Cluster Is a Global Regulator of Tumor Metabolism.
Izreig S, Samborska B, Johnson RM, Sergushichev A, Ma EH, Lussier C, Loginicheva E, Donayo AO, Poffenberger MC, Sagan SM, Vincent EE, Artyomov MN, Duchaine TF, Jones RG. Izreig S, et al. Among authors: jones rg. Cell Rep. 2016 Aug 16;16(7):1915-28. doi: 10.1016/j.celrep.2016.07.036. Epub 2016 Aug 4. Cell Rep. 2016. PMID: 27498867 Free article.
The role of AMPK in T cell metabolism and function.
Ma EH, Poffenberger MC, Wong AH, Jones RG. Ma EH, et al. Among authors: jones rg. Curr Opin Immunol. 2017 Jun;46:45-52. doi: 10.1016/j.coi.2017.04.004. Epub 2017 Apr 28. Curr Opin Immunol. 2017. PMID: 28460345 Review.
LKB1 deficiency in T cells promotes the development of gastrointestinal polyposis.
Poffenberger MC, Metcalfe-Roach A, Aguilar E, Chen J, Hsu BE, Wong AH, Johnson RM, Flynn B, Samborska B, Ma EH, Gravel SP, Tonelli L, Devorkin L, Kim P, Hall A, Izreig S, Loginicheva E, Beauchemin N, Siegel PM, Artyomov MN, Lum JJ, Zogopoulos G, Blagih J, Jones RG. Poffenberger MC, et al. Among authors: jones rg. Science. 2018 Jul 27;361(6400):406-411. doi: 10.1126/science.aan3975. Science. 2018. PMID: 30049881
The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo.
Blagih J, Coulombe F, Vincent EE, Dupuy F, Galicia-Vázquez G, Yurchenko E, Raissi TC, van der Windt GJ, Viollet B, Pearce EL, Pelletier J, Piccirillo CA, Krawczyk CM, Divangahi M, Jones RG. Blagih J, et al. Among authors: jones rg. Immunity. 2015 Jan 20;42(1):41-54. doi: 10.1016/j.immuni.2014.12.030. Epub 2015 Jan 2. Immunity. 2015. PMID: 25607458 Free article.
Oxidative metabolism enables Salmonella evasion of the NLRP3 inflammasome.
Wynosky-Dolfi MA, Snyder AG, Philip NH, Doonan PJ, Poffenberger MC, Avizonis D, Zwack EE, Riblett AM, Hu B, Strowig T, Flavell RA, Jones RG, Freedman BD, Brodsky IE. Wynosky-Dolfi MA, et al. Among authors: jones rg. J Exp Med. 2014 Apr 7;211(4):653-68. doi: 10.1084/jem.20130627. Epub 2014 Mar 17. J Exp Med. 2014. PMID: 24638169 Free PMC article.
411 results