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In situ growth in early lung adenocarcinoma may represent precursor growth or invasive clone outgrowth-a clinically relevant distinction.
Moore DA, Sereno M, Das M, Baena Acevedo JD, Sinnadurai S, Smith C, McSweeney A, Su X, Officer L, Jones C, Dudek K, Guttery D, Taniere P, Spriggs RV, Le Quesne J. Moore DA, et al. Among authors: jones c. Mod Pathol. 2019 Jul;32(8):1095-1105. doi: 10.1038/s41379-019-0257-1. Epub 2019 Apr 1. Mod Pathol. 2019. PMID: 30932019 Free article.
The mTOR regulated RNA-binding protein LARP1 requires PABPC1 for guided mRNA interaction.
Smith EM, Benbahouche NEH, Morris K, Wilczynska A, Gillen S, Schmidt T, Meijer HA, Jukes-Jones R, Cain K, Jones C, Stoneley M, Waldron JA, Bell C, Fonseca BD, Blagden S, Willis AE, Bushell M. Smith EM, et al. Among authors: jones c. Nucleic Acids Res. 2021 Jan 11;49(1):458-478. doi: 10.1093/nar/gkaa1189. Nucleic Acids Res. 2021. PMID: 33332560 Free PMC article.
TAp73 contributes to the oxidative stress response by regulating protein synthesis.
Marini A, Rotblat B, Sbarrato T, Niklison-Chirou MV, Knight JRP, Dudek K, Jones C, Bushell M, Knight RA, Amelio I, Willis AE, Melino G. Marini A, et al. Among authors: jones c. Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):6219-6224. doi: 10.1073/pnas.1718531115. Epub 2018 May 29. Proc Natl Acad Sci U S A. 2018. PMID: 29844156 Free PMC article.
Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target.
Alam MM, Sanchez-Azqueta A, Janha O, Flannery EL, Mahindra A, Mapesa K, Char AB, Sriranganadane D, Brancucci NMB, Antonova-Koch Y, Crouch K, Simwela NV, Millar SB, Akinwale J, Mitcheson D, Solyakov L, Dudek K, Jones C, Zapatero C, Doerig C, Nwakanma DC, Vázquez MJ, Colmenarejo G, Lafuente-Monasterio MJ, Leon ML, Godoi PHC, Elkins JM, Waters AP, Jamieson AG, Álvaro EF, Ranford-Cartwright LC, Marti M, Winzeler EA, Gamo FJ, Tobin AB. Alam MM, et al. Among authors: jones c. Science. 2019 Aug 30;365(6456):eaau1682. doi: 10.1126/science.aau1682. Science. 2019. PMID: 31467193
Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas.
Liko D, Mitchell L, Campbell KJ, Ridgway RA, Jones C, Dudek K, King A, Bryson S, Stevenson D, Blyth K, Strathdee D, Morton JP, Bird TG, Knight JRP, Willis AE, Sansom OJ. Liko D, et al. Among authors: jones c. Cell Death Differ. 2019 Dec;26(12):2535-2550. doi: 10.1038/s41418-019-0316-7. Epub 2019 Mar 11. Cell Death Differ. 2019. PMID: 30858608 Free PMC article.
mTORC1-mediated translational elongation limits intestinal tumour initiation and growth.
Faller WJ, Jackson TJ, Knight JR, Ridgway RA, Jamieson T, Karim SA, Jones C, Radulescu S, Huels DJ, Myant KB, Dudek KM, Casey HA, Scopelliti A, Cordero JB, Vidal M, Pende M, Ryazanov AG, Sonenberg N, Meyuhas O, Hall MN, Bushell M, Willis AE, Sansom OJ. Faller WJ, et al. Among authors: jones c. Nature. 2015 Jan 22;517(7535):497-500. doi: 10.1038/nature13896. Epub 2014 Nov 5. Nature. 2015. PMID: 25383520 Free PMC article.
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