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PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells.
Codarri Deak L, Nicolini V, Hashimoto M, Karagianni M, Schwalie PC, Lauener L, Varypataki EM, Richard M, Bommer E, Sam J, Joller S, Perro M, Cremasco F, Kunz L, Yanguez E, Hüsser T, Schlenker R, Mariani M, Tosevski V, Herter S, Bacac M, Waldhauer I, Colombetti S, Gueripel X, Wullschleger S, Tichet M, Hanahan D, Kissick HT, Leclair S, Freimoser-Grundschober A, Seeber S, Teichgräber V, Ahmed R, Klein C, Umaña P. Codarri Deak L, et al. Among authors: joller s. Nature. 2022 Oct;610(7930):161-172. doi: 10.1038/s41586-022-05192-0. Epub 2022 Sep 28. Nature. 2022. PMID: 36171284 Free PMC article.
The IL-33/ST2 pathway contributes to intestinal tumorigenesis in humans and mice.
Mertz KD, Mager LF, Wasmer MH, Thiesler T, Koelzer VH, Ruzzante G, Joller S, Murdoch JR, Brümmendorf T, Genitsch V, Lugli A, Cathomas G, Moch H, Weber A, Zlobec I, Junt T, Krebs P. Mertz KD, et al. Among authors: joller s. Oncoimmunology. 2015 Jun 26;5(1):e1062966. doi: 10.1080/2162402X.2015.1062966. eCollection 2016. Oncoimmunology. 2015. PMID: 26942077 Free PMC article.
Sustained Trem2 stabilization accelerates microglia heterogeneity and Aβ pathology in a mouse model of Alzheimer's disease.
Dhandapani R, Neri M, Bernhard M, Brzak I, Schweizer T, Rudin S, Joller S, Berth R, Kernen J, Neuhaus A, Waldt A, Cuttat R, Naumann U, Keller CG, Roma G, Feuerbach D, Shimshek DR, Neumann U, Gasparini F, Galimberti I. Dhandapani R, et al. Among authors: joller s. Cell Rep. 2022 May 31;39(9):110883. doi: 10.1016/j.celrep.2022.110883. Cell Rep. 2022. PMID: 35649351 Free article.
Modulation of Microglia by Voluntary Exercise or CSF1R Inhibition Prevents Age-Related Loss of Functional Motor Units.
Giorgetti E, Panesar M, Zhang Y, Joller S, Ronco M, Obrecht M, Lambert C, Accart N, Beckmann N, Doelemeyer A, Perrot L, Fruh I, Mueller M, Pierrel E, Summermatter S, Bidinosti M, Shimshek DR, Brachat S, Nash M. Giorgetti E, et al. Among authors: joller s. Cell Rep. 2019 Nov 5;29(6):1539-1554.e7. doi: 10.1016/j.celrep.2019.10.003. Cell Rep. 2019. PMID: 31693894 Free article.
ADAM17 is the main sheddase for the generation of human triggering receptor expressed in myeloid cells (hTREM2) ectodomain and cleaves TREM2 after Histidine 157.
Feuerbach D, Schindler P, Barske C, Joller S, Beng-Louka E, Worringer KA, Kommineni S, Kaykas A, Ho DJ, Ye C, Welzenbach K, Elain G, Klein L, Brzak I, Mir AK, Farady CJ, Aichholz R, Popp S, George N, Neumann U. Feuerbach D, et al. Among authors: joller s. Neurosci Lett. 2017 Nov 1;660:109-114. doi: 10.1016/j.neulet.2017.09.034. Epub 2017 Sep 18. Neurosci Lett. 2017. PMID: 28923481
Genetic models of cleavage-reduced and soluble TREM2 reveal distinct effects on myelination and microglia function in the cuprizone model.
Beckmann N, Neuhaus A, Zurbruegg S, Volkmer P, Patino C, Joller S, Feuerbach D, Doelemeyer A, Schweizer T, Rudin S, Neumann U, Berth R, Frieauff W, Gasparini F, Shimshek DR. Beckmann N, et al. Among authors: joller s. J Neuroinflammation. 2023 Feb 8;20(1):29. doi: 10.1186/s12974-022-02671-z. J Neuroinflammation. 2023. PMID: 36755323 Free PMC article.
Prospective validation of classification of intraoperative adverse events (ClassIntra): international, multicentre cohort study.
Dell-Kuster S, Gomes NV, Gawria L, Aghlmandi S, Aduse-Poku M, Bissett I, Blanc C, Brandt C, Ten Broek RB, Bruppacher HR, Clancy C, Delrio P, Espin E, Galanos-Demiris K, Gecim IE, Ghaffari S, Gié O, Goebel B, Hahnloser D, Herbst F, Orestis I, Joller S, Kang S, Martín R, Mayr J, Meier S, Murugesan J, Nally D, Ozcelik M, Pace U, Passeri M, Rabanser S, Ranter B, Rega D, Ridgway PF, Rosman C, Schmid R, Schumacher P, Solis-Pena A, Villarino L, Vrochides D, Engel A, O'Grady G, Loveday B, Steiner LA, Van Goor H, Bucher HC, Clavien PA, Kirchhoff P, Rosenthal R. Dell-Kuster S, et al. Among authors: joller s. BMJ. 2020 Aug 25;370:m2917. doi: 10.1136/bmj.m2917. BMJ. 2020. PMID: 32843333 Free PMC article.
15 results