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Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration.
Felszeghy S, Viiri J, Paterno JJ, Hyttinen JMT, Koskela A, Chen M, Leinonen H, Tanila H, Kivinen N, Koistinen A, Toropainen E, Amadio M, Smedowski A, Reinisalo M, Winiarczyk M, Mackiewicz J, Mutikainen M, Ruotsalainen AK, Kettunen M, Jokivarsi K, Sinha D, Kinnunen K, Petrovski G, Blasiak J, Bjørkøy G, Koskelainen A, Skottman H, Urtti A, Salminen A, Kannan R, Ferrington DA, Xu H, Levonen AL, Tavi P, Kauppinen A, Kaarniranta K. Felszeghy S, et al. Among authors: jokivarsi k. Redox Biol. 2019 Jan;20:1-12. doi: 10.1016/j.redox.2018.09.011. Epub 2018 Sep 14. Redox Biol. 2019. PMID: 30253279 Free PMC article.
Impaired Mitochondrial Fatty Acid Synthesis Leads to Neurodegeneration in Mice.
Nair RR, Koivisto H, Jokivarsi K, Miinalainen IJ, Autio KJ, Manninen A, Poutiainen P, Tanila H, Hiltunen JK, Kastaniotis AJ. Nair RR, et al. Among authors: jokivarsi k. J Neurosci. 2018 Nov 7;38(45):9781-9800. doi: 10.1523/JNEUROSCI.3514-17.2018. Epub 2018 Sep 28. J Neurosci. 2018. PMID: 30266742 Free PMC article.
Implantable RF-coil with multiple electrodes for long-term EEG-fMRI monitoring in rodents.
Pirttimäki T, Salo RA, Shatillo A, Kettunen MI, Paasonen J, Sierra A, Jokivarsi K, Leinonen V, Andrade P, Quittek S, Pitkänen A, Gröhn O. Pirttimäki T, et al. Among authors: jokivarsi k. J Neurosci Methods. 2016 Dec 1;274:154-163. doi: 10.1016/j.jneumeth.2016.10.014. Epub 2016 Oct 21. J Neurosci Methods. 2016. PMID: 27777001 Free article.
Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice.
Gabbouj S, Natunen T, Koivisto H, Jokivarsi K, Takalo M, Marttinen M, Wittrahm R, Kemppainen S, Naderi R, Posado-Fernández A, Ryhänen S, Mäkinen P, Paldanius KMA, Doria G, Poutiainen P, Flores O, Haapasalo A, Tanila H, Hiltunen M. Gabbouj S, et al. Among authors: jokivarsi k. Neurobiol Aging. 2019 Mar;75:98-108. doi: 10.1016/j.neurobiolaging.2018.11.008. Epub 2018 Nov 17. Neurobiol Aging. 2019. PMID: 30554086 Free article.
The Alzheimer's disease-associated protective Plcγ2-P522R variant promotes immune functions.
Takalo M, Wittrahm R, Wefers B, Parhizkar S, Jokivarsi K, Kuulasmaa T, Mäkinen P, Martiskainen H, Wurst W, Xiang X, Marttinen M, Poutiainen P, Haapasalo A, Hiltunen M, Haass C. Takalo M, et al. Among authors: jokivarsi k. Mol Neurodegener. 2020 Sep 11;15(1):52. doi: 10.1186/s13024-020-00402-7. Mol Neurodegener. 2020. PMID: 32917267 Free PMC article.
A robust approach to make inorganic nanovectors biotraceable.
Wen H, Närvänen A, Jokivarsi K, Poutiainen P, Xu W, Lehto VP. Wen H, et al. Among authors: jokivarsi k. Int J Pharm. 2022 Aug 25;624:122040. doi: 10.1016/j.ijpharm.2022.122040. Epub 2022 Jul 25. Int J Pharm. 2022. PMID: 35902052 Free article.
36 results