Johnston JN - Search Results

1

Exercise Causes Arrhythmogenic Remodeling of Intracellular Calcium Dynamics in Plakophilin-2-Deficient Hearts.

van Opbergen CJM, Bagwan N, Maurya SR, Kim JC, Smith AN, Blackwell DJ, Johnston JN, Knollmann BC, Cerrone M, Lundby A, Delmar M. van Opbergen CJM, et al. Among authors: johnston jn. Circulation. 2022 May 10;145(19):1480-1496. doi: 10.1161/CIRCULATIONAHA.121.057757. Epub 2022 May 1. Circulation. 2022. PMID: 35491884 Free PMC article.

2

Unnatural verticilide enantiomer inhibits type 2 ryanodine receptor-mediated calcium leak and is antiarrhythmic.

Batiste SM, Blackwell DJ, Kim K, Kryshtal DO, Gomez-Hurtado N, Rebbeck RT, Cornea RL, Johnston JN, Knollmann BC. Batiste SM, et al. Among authors: johnston jn. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):4810-4815. doi: 10.1073/pnas.1816685116. Epub 2019 Feb 21. Proc Natl Acad Sci U S A. 2019. PMID: 30792355 Free PMC article.

3

RYR2 Channel Inhibition Is the Principal Mechanism of Flecainide Action in CPVT.

Kryshtal DO, Blackwell DJ, Egly CL, Smith AN, Batiste SM, Johnston JN, Laver DR, Knollmann BC. Kryshtal DO, et al. Among authors: johnston jn. Circ Res. 2021 Feb 5;128(3):321-331. doi: 10.1161/CIRCRESAHA.120.316819. Epub 2020 Dec 10. Circ Res. 2021. PMID: 33297863 Free PMC article.

4

The Formation of Impossible Rings in Macrocyclooligomerizations for Cyclodepsipeptide Synthesis: The 18-from-12 Paradox.

Smith AN, Johnston JN. Smith AN, et al. Among authors: johnston jn. J Org Chem. 2021 Jun 18;86(12):7904-7919. doi: 10.1021/acs.joc.0c03069. Epub 2021 Jun 7. J Org Chem. 2021. PMID: 34097410 Free PMC article.

5

Ring Size as an Independent Variable in Cyclooligomeric Depsipeptide Antiarrhythmic Activity.

Smith AN, Blackwell DJ, Knollmann BC, Johnston JN. Smith AN, et al. Among authors: johnston jn. ACS Med Chem Lett. 2021 Nov 23;12(12):1942-1947. doi: 10.1021/acsmedchemlett.1c00508. eCollection 2021 Dec 9. ACS Med Chem Lett. 2021. PMID: 34917258 Free PMC article.

6

Resolving Bromonitromethane Sourcing by Synthesis: Preparation at the Decagram Scale.

Thorpe MP, Smith AN, Crocker MS, Johnston JN. Thorpe MP, et al. Among authors: johnston jn. J Org Chem. 2022 Apr 15;87(8):5451-5455. doi: 10.1021/acs.joc.2c00405. Epub 2022 Apr 1. J Org Chem. 2022. PMID: 35364809 Free PMC article.

7

Structure-Activity Relationships for the N-Me- Versus N-H-Amide Modification to Macrocyclic ent-Verticilide Antiarrhythmics.

Smith AN, Thorpe MP, Blackwell DJ, Batiste SM, Hopkins CR, Schley ND, Knollmann BC, Johnston JN. Smith AN, et al. Among authors: johnston jn. ACS Med Chem Lett. 2022 Oct 5;13(11):1755-1762. doi: 10.1021/acsmedchemlett.2c00377. eCollection 2022 Nov 10. ACS Med Chem Lett. 2022. PMID: 36385927 Free PMC article.

8

RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET.

Šeflová J, Schwarz JA, Smith AN, Svensson B, Blackwell DJ, Phillips TA, Nikolaienko R, Bovo E, Rebbeck RT, Zima AV, Thomas DD, Van Petegem F, Knollmann BC, Johnston JN, Robia SL, Cornea RL. Šeflová J, et al. Among authors: johnston jn. ACS Chem Biol. 2023 Oct 20;18(10):2290-2299. doi: 10.1021/acschembio.3c00376. Epub 2023 Sep 28. ACS Chem Biol. 2023. PMID: 37769131

9

Enantioselective Synthesis of cis- and trans-Cycloheptyl β-Fluoro Amines by Sequential aza-Henry Addition/Ring-Closing Metathesis.

Bing JA, Johnston JN. Bing JA, et al. Among authors: johnston jn. Org Lett. 2023 Feb 17;25(6):950-955. doi: 10.1021/acs.orglett.2c04285. Epub 2023 Feb 3. Org Lett. 2023. PMID: 36735762 Free PMC article.

10

1,3,4-Oxadiazole and Heteroaromatic-Fused 1,2,4-Triazole Synthesis using Diverted Umpolung Amide Synthesis.

Tokumaru K, Bera K, Johnston JN. Tokumaru K, et al. Among authors: johnston jn. Synthesis (Stuttg). 2017 Oct;49(20):4670-4675. doi: 10.1055/s-0036-1590802. Epub 2017 Aug 7. Synthesis (Stuttg). 2017. PMID: 29507449 Free PMC article.

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