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Inhibition of Pannexin 1 Reduces the Tumorigenic Properties of Human Melanoma Cells.
Freeman TJ, Sayedyahossein S, Johnston D, Sanchez-Pupo RE, O'Donnell B, Huang K, Lakhani Z, Nouri-Nejad D, Barr KJ, Harland L, Latosinsky S, Grant A, Dagnino L, Penuela S. Freeman TJ, et al. Among authors: johnston d. Cancers (Basel). 2019 Jan 16;11(1):102. doi: 10.3390/cancers11010102. Cancers (Basel). 2019. PMID: 30654593 Free PMC article.
Targeting FER Kinase Inhibits Melanoma Growth and Metastasis.
Ivanova IA, Arulanantham S, Barr K, Cepeda M, Parkins KM, Hamilton AM, Johnston D, Penuela S, Hess DA, Ronald JA, Dagnino L. Ivanova IA, et al. Among authors: johnston d. Cancers (Basel). 2019 Mar 24;11(3):419. doi: 10.3390/cancers11030419. Cancers (Basel). 2019. PMID: 30909648 Free PMC article.
Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein.
Nouri-Nejad D, O'Donnell BL, Patil CS, Sanchez-Pupo RE, Johnston D, Sayedyahossein S, Jurcic K, Lau R, Gyenis L, Litchfield DW, Jackson MF, Gloor GB, Penuela S. Nouri-Nejad D, et al. Among authors: johnston d. Mol Biol Cell. 2021 Mar 1;32(5):376-390. doi: 10.1091/mbc.E19-10-0585. Epub 2021 Jan 6. Mol Biol Cell. 2021. PMID: 33405952 Free PMC article.
Pannexin 1 binds β-catenin to modulate melanoma cell growth and metabolism.
Sayedyahossein S, Huang K, Li Z, Zhang C, Kozlov AM, Johnston D, Nouri-Nejad D, Dagnino L, Betts DH, Sacks DB, Penuela S. Sayedyahossein S, et al. Among authors: johnston d. J Biol Chem. 2021 Jan-Jun;296:100478. doi: 10.1016/j.jbc.2021.100478. Epub 2021 Feb 26. J Biol Chem. 2021. PMID: 33647315 Free PMC article.
Pannexin 3 deletion reduces fat accumulation and inflammation in a sex-specific manner.
Wakefield CB, Lee VR, Johnston D, Boroumand P, Pillon NJ, Sayedyahossein S, O'Donnell BL, Tang J, Sanchez-Pupo RE, Barr KJ, Gros R, Flynn L, Borradaile NM, Klip A, Beier F, Penuela S. Wakefield CB, et al. Among authors: johnston d. Int J Obes (Lond). 2022 Apr;46(4):726-738. doi: 10.1038/s41366-021-01037-4. Epub 2021 Dec 13. Int J Obes (Lond). 2022. PMID: 34897286
3,241 results