Johnson TB - Search Results

1

AAV9 Gene Therapy Increases Lifespan and Treats Pathological and Behavioral Abnormalities in a Mouse Model of CLN8-Batten Disease.

Johnson TB, White KA, Brudvig JJ, Cain JT, Langin L, Pratt MA, Booth CD, Timm DJ, Davis SS, Meyerink B, Likhite S, Meyer K, Weimer JM. Johnson TB, et al. Mol Ther. 2021 Jan 6;29(1):162-175. doi: 10.1016/j.ymthe.2020.09.033. Epub 2020 Sep 24. Mol Ther. 2021. PMID: 33010819 Free PMC article.

2

Characterization of a recurrent missense mutation in the forkhead DNA-binding domain of FOXP1.

Johnson TB, Mechels K, Anderson RH, Cain JT, Sturdevant DA, Braddock S, Pinz H, Wilson MA, Landsverk M, Roux KJ, Weimer JM. Johnson TB, et al. Sci Rep. 2018 Nov 1;8(1):16161. doi: 10.1038/s41598-018-34437-0. Sci Rep. 2018. PMID: 30385778 Free PMC article.

3

Tracking sex-dependent differences in a mouse model of CLN6-Batten disease.

Poppens MJ, Cain JT, Johnson TB, White KA, Davis SS, Laufmann R, Kloth AD, Weimer JM. Poppens MJ, et al. Among authors: johnson tb. Orphanet J Rare Dis. 2019 Jan 21;14(1):19. doi: 10.1186/s13023-019-0994-8. Orphanet J Rare Dis. 2019. PMID: 30665444 Free PMC article.

4

Therapeutic landscape for Batten disease: current treatments and future prospects.

Johnson TB, Cain JT, White KA, Ramirez-Montealegre D, Pearce DA, Weimer JM. Johnson TB, et al. Nat Rev Neurol. 2019 Mar;15(3):161-178. doi: 10.1038/s41582-019-0138-8. Nat Rev Neurol. 2019. PMID: 30783219 Free PMC article. Review.

5

Gene Therapy Corrects Brain and Behavioral Pathologies in CLN6-Batten Disease.

Cain JT, Likhite S, White KA, Timm DJ, Davis SS, Johnson TB, Dennys-Rivers CN, Rinaldi F, Motti D, Corcoran S, Morales P, Pierson C, Hughes SM, Lee SY, Kaspar BK, Meyer K, Weimer JM. Cain JT, et al. Among authors: johnson tb. Mol Ther. 2019 Oct 2;27(10):1836-1847. doi: 10.1016/j.ymthe.2019.06.015. Epub 2019 Jul 10. Mol Ther. 2019. PMID: 31331814 Free PMC article.

6

Changes in motor behavior, neuropathology, and gut microbiota of a Batten disease mouse model following administration of acidified drinking water.

Johnson TB, Langin LM, Zhao J, Weimer JM, Pearce DA, Kovács AD. Johnson TB, et al. Sci Rep. 2019 Oct 18;9(1):14962. doi: 10.1038/s41598-019-51488-z. Sci Rep. 2019. PMID: 31628420 Free PMC article.

7

A multimodal approach to identify clinically relevant biomarkers to comprehensively monitor disease progression in a mouse model of pediatric neurodegenerative disease.

Johnson TB, Brudvig JJ, Lehtimäki KK, Cain JT, White KA, Bragge T, Rytkönen J, Huhtala T, Timm D, Vihma M, Puoliväli JT, Poutiainen P, Nurmi A, Weimer JM. Johnson TB, et al. Prog Neurobiol. 2020 Jun;189:101789. doi: 10.1016/j.pneurobio.2020.101789. Epub 2020 Mar 18. Prog Neurobiol. 2020. PMID: 32198061

8

Author Correction: Characterization of a recurrent missense mutation in the forkhead DNA-binding domain of FOXP1.

Johnson TB, Mechels K, Anderson RH, Cain JT, Sturdevant DA, Braddock S, Pinz H, Wilson MA, Landsverk M, Roux KJ, Weimer JM. Johnson TB, et al. Sci Rep. 2020 Apr 15;10(1):6635. doi: 10.1038/s41598-020-62950-8. Sci Rep. 2020. PMID: 32296074 Free PMC article.

9

A tailored Cln3^Q352X mouse model for testing therapeutic interventions in CLN3 Batten disease.

Langin L, Johnson TB, Kovács AD, Pearce DA, Weimer JM. Langin L, et al. Among authors: johnson tb. Sci Rep. 2020 Jun 29;10(1):10591. doi: 10.1038/s41598-020-67478-5. Sci Rep. 2020. PMID: 32601357 Free PMC article.

10

Therapeutic efficacy of antisense oligonucleotides in mouse models of CLN3 Batten disease.

Centa JL, Jodelka FM, Hinrich AJ, Johnson TB, Ochaba J, Jackson M, Duelli DM, Weimer JM, Rigo F, Hastings ML. Centa JL, et al. Among authors: johnson tb. Nat Med. 2020 Sep;26(9):1444-1451. doi: 10.1038/s41591-020-0986-1. Epub 2020 Jul 27. Nat Med. 2020. PMID: 32719489 Free PMC article.

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