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Cas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair.
Webber BR, Johnson MJ, Skeate JG, Slipek NJ, Lahr WS, DeFeo AP, Mills LJ, Qiu X, Rathmann B, Diers MD, Wick B, Henley T, Choudhry M, Starr TK, McIvor RS, Moriarity BS. Webber BR, et al. Among authors: johnson mj. Nat Biomed Eng. 2023 Dec 13. doi: 10.1038/s41551-023-01157-4. Online ahead of print. Nat Biomed Eng. 2023. PMID: 38092857
Author Correction: Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors.
Webber BR, Lonetree CL, Kluesner MG, Johnson MJ, Pomeroy EJ, Diers MD, Lahr WS, Draper GM, Slipek NJ, Smeester BA, Lovendahl KN, McElroy AN, Gordon WR, Osborn MJ, Moriarity BS. Webber BR, et al. Among authors: johnson mj. Nat Commun. 2019 Dec 6;10(1):5659. doi: 10.1038/s41467-019-13778-y. Nat Commun. 2019. PMID: 31811147 Free PMC article.
Genome Engineering of Primary Human B Cells Using CRISPR/Cas9.
Laoharawee K, Johnson MJ, Lahr WS, Peterson JJ, Webber BR, Moriarity BS. Laoharawee K, et al. Among authors: johnson mj. J Vis Exp. 2020 Nov 3;(165):10.3791/61855. doi: 10.3791/61855. J Vis Exp. 2020. PMID: 33226023 Free PMC article.
Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade.
Palmer DC, Webber BR, Patel Y, Johnson MJ, Kariya CM, Lahr WS, Parkhurst MR, Gartner JJ, Prickett TD, Lowery FJ, Kishton RJ, Gurusamy D, Franco Z, Vodnala SK, Diers MD, Wolf NK, Slipek NJ, McKenna DH, Sumstad D, Viney L, Henley T, Bürckstümmer T, Baker O, Hu Y, Yan C, Meerzaman D, Padhan K, Lo W, Malekzadeh P, Jia L, Deniger DC, Patel SJ, Robbins PF, McIvor RS, Choudhry M, Rosenberg SA, Moriarity BS, Restifo NP. Palmer DC, et al. Among authors: johnson mj. Med. 2022 Oct 14;3(10):682-704.e8. doi: 10.1016/j.medj.2022.07.008. Epub 2022 Aug 24. Med. 2022. PMID: 36007524 Free PMC article.
mTOR regulates metabolic adaptation of APCs in the lung and controls the outcome of allergic inflammation.
Sinclair C, Bommakanti G, Gardinassi L, Loebbermann J, Johnson MJ, Hakimpour P, Hagan T, Benitez L, Todor A, Machiah D, Oriss T, Ray A, Bosinger S, Ravindran R, Li S, Pulendran B. Sinclair C, et al. Among authors: johnson mj. Science. 2017 Sep 8;357(6355):1014-1021. doi: 10.1126/science.aaj2155. Epub 2017 Aug 10. Science. 2017. PMID: 28798047 Free PMC article.
723 results